脱细胞膀胱基质补片的生物相容性研究
发布时间：2019-06-28 09:54
【摘要】：目的评价脱细胞膀胱基质作为盆底修复替代材料的生物相容性。方法通过细胞毒性试验、溶血试验、阴道埋植试验等体内外生物学实验相结合的方法评价该材料的生物相容性。结果在细胞毒性试验中,材料毒性级别0~1级。材料浸提液的溶血率为1.5%。大体和组织学观察示材料未引起宿主免疫排斥反应,植入后引起轻度的异物反应,移植12周后基本降解。结论该材料具有良好的生物相容性,但需调整其降解率,以适应盆底修复手术要求。
[Abstract]:Objective to evaluate the biocompatibility of acellular bladder matrix as an alternative material for pelvic floor repair. Methods the biocompatibility of the material was evaluated by cytotoxicity test, hemolysis test, vaginal implantation test and other biological experiments in vitro and in vivo. Results in the cytotoxicity test, the toxicity grade of the material was 0 鈮，
本文编号：2507203
[Abstract]:Objective to evaluate the biocompatibility of acellular bladder matrix as an alternative material for pelvic floor repair. Methods the biocompatibility of the material was evaluated by cytotoxicity test, hemolysis test, vaginal implantation test and other biological experiments in vitro and in vivo. Results in the cytotoxicity test, the toxicity grade of the material was 0 鈮，
本文编号：2507203
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