沧州市39356例新生儿听力筛查结果分析

发布时间：2017-12-30 18:17

  本文关键词：沧州市39356例新生儿听力筛查结果分析　出处：《听力学及言语疾病杂志》2016年01期 　论文类型：期刊论文

  更多相关文章： 新生儿 听力筛查 听力损失 基因

【摘要】：目的了解沧州市新生儿听力筛查状况。方法应用DPOAE对沧州市2013~2014年出生新生儿(不包括高危儿)进行听力筛查,初筛未通过者42天进行复筛,复筛未通过者3个月进行听力诊断,对于诊断听力损失者进行GJB2、GJB3、SLC26A4、mtDNA 12SrRNA四个常见耳聋基因突变筛查。结果沧州市2013~2014年共出生新生儿44 456例,完成初筛的新生儿为39 356例(88.53%,39 356/44 456),初筛未通过5 437例(13.81%,5 437/39 356),复筛2 153例(39.60%,2 153/5 437),复筛未通过215例(9.99%,215/2 153),转诊进行听力诊断者71例(33.02%,71/215),确诊听力损失48例,其中单耳听力损失20例中,轻度听力损失13例,中度听力损失5例,极重度听力损失2例;双耳听力损失28例中,轻度-中度听力损失18例,重度以上听力损失10例,听力损失检出率1.22‰(48/39 356);这48例中,13例(27.08%,13/48)耳聋基因筛查阳性。结论沧州市2013~2014两年新生儿听力损失检出率为1.22‰,复筛率和转诊率均较低。
[Abstract]:Objective to investigate the status of neonatal hearing screening in Cangzhou. Methods DPOAE was used to screen the hearing of newborns (excluding high-risk infants) born in Cangzhou from 2013 to 2014. The patients who had not passed the primary screening were screened again for 42 days, the patients who failed the screening were diagnosed by hearing for 3 months, and the patients with hearing loss were diagnosed with GJB _ 2, GJB _ 3 and SLC26A4. MtDNA 12s rRNA was screened for four common deafness gene mutations. Results 44,456 newborns were born in Cangzhou from 2013 to 2014. The total number of newborns who completed the primary screening was 39 356/44 456m (39 356 / 88.53), and the primary screening failed 5 437 cases (13.81%). 5 437/39 356m, 2153 cases of double sieve, 2 153/5 437m, 21515 / 2153). Among the 71 cases who were referred for hearing diagnosis, there were 71 cases (33.02%) diagnosed hearing loss, 48 cases were confirmed hearing loss, of which 20 cases were single ear hearing loss, 13 cases were mild hearing loss and 5 cases were moderate hearing loss. Very severe hearing loss in 2 cases; Among the 28 cases of binaural hearing loss, there were 18 cases of mild to moderate hearing loss and 10 cases of severe hearing loss. The detection rate of hearing loss was 1.22 鈥，

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