阻塞性睡眠呼吸暂停低通气综合征患者的MPV、PDW和RDW的相关性研究

发布时间：2018-01-03 04:34

本文关键词：阻塞性睡眠呼吸暂停低通气综合征患者的MPV、PDW和RDW的相关性研究　出处：《延边大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：探讨不同程度OSAHS患者的平均血小板体积(MPV)、血小板分布宽度(PDW)、红细胞分布宽度(RDW)之间的相关性。方法：本研究随机选取从2013年10月到2015年10月于延边大学附属医院耳鼻咽喉科就诊的194位睡眠打鼾患者作为研究对象。记录每一个受试者的身高和体重及MPV,PDW,RDW,并对每一个受试者做多导睡眠监测。研究对象根据呼吸紊乱指数(AHI)分为如下四个组：1)阴性对照组：AHI5；2)轻度组：5AHI15; 3)中度组：15AHI30; 4)重度组：AHI≥30。结果：1)与阴性对照组相比,MPV及PDW随着OSAHS严重程度的增加而增加(P0.01),而RDW和身体质量指数(BMI)在轻、中、重度OSAHS患者中无显著性差异(P0.05)。2)PDW与MPV (r=0.94,P0.05), AHI与MPV(r=0.58,P0.0001), AHI与PDW (r=0.57,P0.0001)之间均有正相关性。结论：1)MPV和PDW独立地与OSAHS患者疾病严重程度呈正相关；2)RDW与OSAHS的严重程度无相关性。
[Abstract]:Objective: to investigate the mean platelet volume (MPV) and platelet distribution width (PDW) in patients with OSAHS. RDW). Methods:. From October 2013 to October 2015, 194 patients with sleep snoring from the Department of Otolaryngology, affiliated Hospital of Yanbian University were randomly selected as the study subjects. The height of each participant was recorded. And weight and MPV. The subjects were divided into four groups according to the respiratory disorder index (AHII) as follows: 1) negative control group: AHI5; 2) mild group: 5AHI15; 3) medium group: 15 AHI 30; 4) in severe group, PDW and MPV increased with the increase of OSAHS severity (P 0.01). However, there was no significant difference between RDW and BMI in mild, moderate and severe OSAHS patients. AHI and MPV ~ (0.58) P 0.0001, AHI and PDW ~ (0.57). Conclusion both PDW and MPV have a positive correlation with the severity of disease in patients with OSAHS. 2 there was no correlation between RDW and severity of OSAHS.
【学位授予单位】：延边大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R766

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