曲伏前列素滴眼液治疗原发性开角型青光眼和高眼压症

发布时间：2018-01-04 16:27

本文关键词：曲伏前列素滴眼液治疗原发性开角型青光眼和高眼压症　出处：《国际眼科杂志》2016年12期 　论文类型：期刊论文

【摘要】：目的:研究曲伏前列素滴眼液治疗原发性开角型青光眼和高眼压症的降眼压效果及安全性。方法:随机选取2013-03/2016-03我院收治的原发性开角型青光眼和高眼压症患者80例80眼,依据不同治疗方法分为两组:曲伏前列素滴眼液组(n=40)和拉坦前列素滴眼液组(n=40),对两组患者的临床疗效、视力、散光度、眼压及不良反应发生情况进行统计分析。结果:曲伏前列素滴眼液组患者治疗的总有效率95%(38/40)显著高于拉坦前列素滴眼液组80%(32/40),差异有统计学意义(P0.05)。曲伏前列素滴眼液组患者治疗后视力显著高于拉坦前列素滴眼液组,差异有统计学意义(P0.05),散光度、眼压均显著低于拉坦前列素滴眼液组,差异有统计学意义(P0.05),不良反应发生率25%(10/40)显著低于拉坦前列素滴眼液组53%(21/40),差异有统计学意义(P0.05)。结论:曲伏前列素滴眼液治疗原发性开角型青光眼和高眼压症比拉坦前列素滴眼液具有较好的降眼压效果及较高的安全性。
[Abstract]:Objective: To study the effect of lowering intraocular pressure and safety of Travoprost Eye Drops in the treatment of primary open-angle glaucoma and ocular hypertension. Methods: randomly selected in our hospital 2013-03/2016-03 primary open-angle glaucoma and ocular hypertension in 80 eyes of 80 patients, according to the different treatment methods were divided into two groups: Travoprost Eye Drops group (n=40) and Latanoprost Eye Drops group (n=40), the clinical curative effect, two groups of patients with visual acuity, astigmatism, intraocular pressure and statistical analysis of incidence of adverse reactions. Results: the total efficiency of 95% Travoprost Eye Drops group (38/40) was significantly higher than that of Latanoprost Eye Drops group 80% (32/40), the difference was statistically significant (P0.05). The vision of Travoprost Eye Drops group patients after treatment was significantly higher than that of the Latanoprost Eye Drops group, the difference was statistically significant (P0.05), astigmatism, intraocular pressure was significantly lower than that of latanoprost Hormone eyedrop group, the difference was statistically significant (P0.05), the incidence of adverse reactions was 25% (10/40) was significantly lower than that of Latanoprost Eye Drops group 53% (21/40), the difference was statistically significant (P0.05). Conclusion: the safety of Travoprost Eye Drops in the treatment of primary open-angle glaucoma and ocular hypertension vilatan latanoprost eye drops is reduced the intraocular pressure effect and better.

【作者单位】：武警浙江省总队医院嘉兴医院眼科;
【分类号】：R775
【正文快照】： 0 引言现阶段,临床采用的降低眼压的方法为0.05g/L拉坦前列素滴眼液等前列腺素制剂,由于其具有较好的降眼压效果、较少的不良反应及用药次数,因此在临床得到了极为广泛的应用[1]。曲伏前列素属于一种新的前列腺素制剂,对FP前列腺类受体选择性较高,具有显著较高的效果。FP前

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