老年起病的糖尿病患者视网膜病变患病风险的研究

发布时间：2018-01-16 01:19

本文关键词：老年起病的糖尿病患者视网膜病变患病风险的研究　出处：《西南国防医药》2016年11期 　论文类型：期刊论文

【摘要】：目的探讨老年起病的糖尿病患者视网膜病变(DR)的患病风险。方法纳入在我院住院的糖尿病患者1787例,均行眼底检查,根据糖尿病初诊年龄将患者分为3组:45岁组、45~65岁组、65岁组,每组再按照病程分为3个亚组:病程5~10年、10~15年、15年。比较在相同病程下,不同初诊年龄组的DR患病率以及严重程度。结果本研究1787例中,诊断DR有779(43.6%)例,其中,增殖期视网膜病变(PDR)有229(12.8%)例。在相同病程情况下,DR患病率随着初诊年龄的增加而降低,初诊年龄65岁组的DR患病率最低。与初诊年龄45岁组相比,初诊年龄65岁组PDR患病风险显著降低[病程5~10年:OR(95%CI),0.23(0.07~0.73);病程10~15年:0.05(0.01~0.37);病程15年:0.10(0.01~0.69)]。结论在相同病程情况下,老年起病的糖尿病患者PDR的患病风险明显低于青壮年起病的糖尿病患者。
[Abstract]:Objective to investigate the risk of diabetic retinopathy (DRV) in elderly diabetic patients. Methods 1787 diabetic patients in our hospital underwent fundus examination. The patients were divided into 3 groups according to the age of first diagnosis of diabetes mellitus. Each group was divided into 3 subgroups according to the course of disease: the course of disease was 5 ~ 10 years and 10 ~ 15 years. 15 years. To compare the prevalence and severity of Dr in different age groups with the same course of disease. Results in this study, there were 779 / 43.6 (779 / 43.6) cases of Dr diagnosed in this study. In the same course of disease, the prevalence of Dr decreased with the increase of age. Dr prevalence was the lowest in 65 years old group, and the risk of PDR in 65 years old group was significantly lower than that in 45 years old group. [The disease course ranged from 5 to 10 years. The course of disease ranged from 10 to 15 years. Conclusion under the same course of disease, the risk of PDR in the elderly patients with diabetes is significantly lower than that in the young patients with diabetes.
【作者单位】：四川大学华西医院内分泌科;
【分类号】：R587.2;R774.1
【正文快照】： 糖尿病视网膜病变(DR)是糖尿病最常见的微血管并发症,是成年人失明最主要的病因[1]。DR的危险因素主要包括高血糖、糖尿病病程和高血压等[2]。糖尿病控制和并发症试验(DCCT)及英国前瞻性糖尿病研究(UKPDS)均表明,严格控制血糖可以显著减少DR发生和进展[3-4]。但是,美国控制糖

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