天眩清注射液辅助治疗梅尼埃病的临床观察

发布时间：2018-02-25 19:31

本文关键词： 天眩清注射液辅助治疗梅尼埃病临床效果　出处：《中国药房》2016年14期 　论文类型：期刊论文

【摘要】：目的:观察中药制剂天眩清注射液辅助常规西医治疗梅尼埃病的临床疗效及安全性。方法:采用回顾性分析,选取102例确诊为梅尼埃病的患者,根据治疗方法不同分为研究组53例、对照组49例,两组患者均给予西医常规治疗(低分子右旋糖酐500 ml加三磷酸腺苷、辅酶A静脉滴注,qd,并口服地西泮),研究组患者在此基础上给予天眩清注射液600 mg加入5%葡萄糖注射液或0.9%氯化钠注射液中,ivgtt,qd,辅助治疗。7 d为1个疗程,两组患者均治疗2个疗程。结果:治疗后,两组患者的眩晕障碍量表(DHI)评分较治疗前降低,且研究组显著低于对照组,差异有统计学意义(P0.05);治疗后研究组患者的眩晕症状治疗总有效率(83.02%)显著高于对照组(61.22%),差异有统计学意义(P0.05);研究组患者的听力改善率(88.68%)亦显著高于对照组(73.47%),差异有统计学意义(P0.05)。两组患者均未见明显不良反应。结论:中药制剂天眩清注射液辅助常规西医治疗梅尼埃病的临床疗效显著,且可显著改善患者的眩晕和听力症状,安全性好。
[Abstract]:Objective: to observe the clinical efficacy and safety of Tianxuan Qing injection, a traditional Chinese medicine preparation, in the treatment of Meniere's disease. Methods: 102 patients with Meniere's disease were selected by retrospective analysis. According to different treatment methods, 53 cases in study group and 49 cases in control group were divided into two groups. Both patients in both groups were given routine western medicine treatment (500 ml low molecular dextran plus adenosine triphosphate, Coenzyme A was infused intravenously with diazepam. On this basis, patients in the study group were given Tianxuanqing injection 600mg plus 5% glucose injection or 0.9% sodium chloride injection iv gtttqd.The adjuvant therapy was 7 days as a course of treatment. Results: after treatment, the scores of dizziness scale (DHI) in both groups were lower than those before treatment, and the scores in the study group were significantly lower than those in the control group. After treatment, the total effective rate of vertigo in the study group was 83.02) significantly higher than that in the control group (P 0.05). The hearing improvement rate of the study group was also significantly higher than that of the control group (73.47%). There were no obvious adverse reactions between the two groups. Conclusion: the therapeutic effect of Tianxuanqing injection on Meniere's disease is remarkable. And can significantly improve the vertigo and hearing symptoms of patients with good safety.
【作者单位】：苏州大学附属第二医院耳鼻咽喉科;
【分类号】：R764.33

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