儿童及成人中间型葡萄膜炎临床过程及预后对比研究

发布时间：2018-02-28 16:28

本文关键词： 儿童成人中间型葡萄膜炎预后　出处：《眼科新进展》2017年07期 　论文类型：期刊论文

【摘要】：目的探讨儿童及成人中间型葡萄膜炎临床过程及预后对比。方法选取我院2012年1月至2014年12月收治的121例中间型葡萄膜炎患者作为研究对象,其中单眼受累67例、双眼受累54例;儿童59例、成人62例;依据病情严重程度予以个性化用药方案进行治疗,比较不同眼部受累患者以及儿童与成人的治疗效果和预后。结果单眼受累患者治疗总有效率92.5%,双眼受累患者治疗总有效率92.6%;儿童治疗总有效率93.2%,成人治疗总有效率91.9%,组间差异均无统计学意义(均为P0.05);不同眼部受累患者及儿童与成人治疗前急性时相蛋白、视力组间差异均无统计学意义(均为P0.05),治疗后各指标比较,组间差异均无统计学意义(均为P0.05)。各组治疗后急性时相蛋白水平均降低且视力明显提高,组内治疗前后比较差异均有统计学意义(均为P0.05)。结论给予中间型葡萄膜炎患者个体化治疗方案将能够显著提高治疗效果、控制炎症以及提高视力水平,但其疗效与年龄、眼部受累程度并无明显影响关系。
[Abstract]:Objective to investigate the clinical process and prognosis of intermediate uveitis in children and adults. Methods 121 patients with intermediate uveitis were selected from January 2012 to December 2014 in our hospital. There were 54 cases of binocular involvement, 59 cases of children and 62 cases of adults. Results the total effective rate was 92.5 in patients with monocular involvement, 92.6in patients with binocular involvement, 93.2in children and 93.2 in adults. There was no significant difference between the two groups (all P 0.05), the acute phase proteins of patients with different ocular involvement and children and adults before treatment were not statistically significant. There was no significant difference in visual acuity between the two groups (all P 0.05). There was no significant difference between the two groups (all P 0.05). The acute phase protein level decreased and the visual acuity improved significantly after treatment. There were significant differences between the two groups before and after treatment (P 0.05). Conclusion the individualized treatment regimen for patients with intermediate uveitis can significantly improve the therapeutic effect, control inflammation and improve visual acuity, but its curative effect and age can be improved. The degree of ocular involvement is not significantly related to the degree of ocular involvement.
【作者单位】：湖北医药学院附属襄阳医院;
【分类号】：R773.9

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