经鼻吸入布地奈德气雾剂同步治疗小儿变应性鼻炎并发哮喘的临床疗效与成本

发布时间：2018-03-01 17:55

本文关键词： 变应性鼻炎支气管哮喘布地奈德经鼻吸入疗效　出处：《中国处方药》2016年12期 　论文类型：期刊论文

【摘要】：目的评价经鼻吸入布地奈德气雾剂同步治疗小儿变应性鼻炎(AR)并发哮喘(BA)的临床疗效及成本。方法选取2012年1月~2015年12月接受治疗的AR并发BA患儿88例,随机分为对照组和观察组各44例,分别采用经口和经鼻吸入布地奈德气雾剂进行治疗。比较两组的临床疗效及治疗成本。结果治疗后,两组患儿的鼻炎症状记分、哮喘症状记分、FEV1、PEF变异率、血清TIg E、ECP和IL-5均较治疗前明显改善(P0.05),而观察组改善幅度更大,差异有统计学意义(P0.05);观察组治疗成本(241.19±17.24)元,显著低于对照组,差异有统计学意义(P0.05)。结论经鼻吸入布地奈德气雾剂同步治疗AR并发BA,可有效改善患者的肺功能及免疫功能,疗效确切,且治疗成本低廉。
[Abstract]:Objective to evaluate the clinical efficacy and cost of inhaled budesonide aerosol in the treatment of children with allergic rhinitis complicated with asthma and BA.Methods 88 cases of AR complicated with BA were treated from January 2012 to December 2015. Patients in the control group and the observation group were randomly divided into two groups: 44 cases in each group were treated by oral and nasal inhalation of budesonide aerosol respectively. The clinical efficacy and cost of treatment were compared between the two groups. Results after treatment, the scores of rhinitis symptoms were recorded in the two groups. The variation rate of FEV1 / PEF, serum TIg and IL-5 were significantly improved in the observation group than before treatment, but the improvement was more significant in the observation group (P 0.05), and the treatment cost in the observation group was 241.19 卤17.24 yuan, which was significantly lower than that in the control group. Conclusion simultaneous nasal inhalation of budesonide aerosol can effectively improve the pulmonary function and immune function of patients with AR complicated with BA.Conclusion the curative effect is accurate and the cost of treatment is low.
【作者单位】：十堰市铁路医院;
【分类号】：R725.6;R765.21

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