散瞳对Pentacam测量眼前节参数的影响

发布时间：2018-03-10 15:45

本文选题：Pentacam　切入点：散瞳　出处：《广西医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨散瞳对Pentacam测量人眼眼前段形态的影响,分析比较各个参数测量值,为临床工作提供一定的参考依据。方法:前瞻性研究。选择2017年1月至2017年3月在我院眼科门诊就诊的近视眼患者51例(102眼),年龄相关性白内障患者40例(71眼),另外征集正常眼患者20例(40眼),应用pentacam眼前节分析系统获取散瞳(复方托吡卡胺滴眼液)前后的眼前节形态学参数。数据的统计使用SPSS17.0统计软件包。结果:(1)正常眼、近视眼组:瞳孔直径(PD)、中央角膜厚度(CCT)、最薄点角膜厚度(TCT)、前房容积(ACV)、中央前房深度(ACD)均较散瞳前增大,结果有统计学意义(P0.05));角膜前后表面水平轴曲率(Rh)、前后表面垂直轴曲率(Rv)、角膜前后表面平均曲率(Rm)、角膜前后表面Q值、Kappa角(X轴)、前房角(ACA)、角膜总高阶像差(RMSh)、角膜三阶水平慧差(Z_3~1)、角膜三阶垂直慧差(Z_3~(-1))、角膜球差(Z_4~0)散瞳前后差异无统计学意义(P0.05)。(2)年龄相关性白内障组:瞳孔直径(PD)、最薄点角膜厚度(TCT)、前房容积(ACV)、中央前房深度(ACD)、前房角(ACA)均较散瞳前增大,结果有统计学意义(P0.05));中央角膜厚度(CCT)、角膜前后表面水平轴曲率(Rh)、前后表面垂直轴曲率(Rv)、角膜前后表面平均曲率(Rm)、角膜前后表面Q值、Kappa角(X轴)、角膜总高阶像差(RMSh)、角膜三阶水平慧差(Z_3~1)、角膜三阶垂直慧差(Z_3~(-1))、角膜球差(Z_4~0)散瞳前后差异无统计学意义(P0.05)。(3)全部研究对象合并后:瞳孔直径(PD)、中央角膜厚度(CCT)、最薄点角膜厚度(TCT)、前房容积(ACV)、中央前房深度(ACD)、Kappa角(X轴)、前房角(ACA)均较散瞳前增大,结果有统计学意义(P0.05));角膜前后表面水平轴曲率(Rh)、前后表面垂直轴曲率(Rv)、前后表面平均轴曲率(Rm)、角膜前后表面Q值、、角膜总高阶像差(RMSh)、角膜三阶水平慧差(Z_3~1)、角膜三阶垂直慧差(Z_3~(-1))、角膜球差(Z_4~0)散瞳前后差异无统计学意义(P0.05)。结论:正常眼、近视眼组散瞳后,瞳孔直径、中央角膜厚度及最薄点角膜厚度增加,前房深度加深,前房容积加大;白内障组散瞳后,瞳孔直径、最薄点角膜厚度、中央前房深度变深,前房容积增加。散瞳前后各组角膜曲率、角膜像差等无明显改变。建议最好在非散瞳条件下进行检查;如确需应用在散瞳下测量的结果,建议结合临床实际进行具体分析,选取对测量参数没有影响的数据进行应用。
[Abstract]:Objective: to investigate the effect of pupil dilation on the morphology of anterior segment of human eye measured by Pentacam, and to analyze and compare the measured values of each parameter. Methods: from January 2017 to March 2017, 51 patients with myopia and 71 eyes with age-related cataract were enrolled in our hospital from January 2017 to March 2017. In addition, the morphological parameters of anterior and posterior mydriasis (compound topiramine eye drops) before and after mydriasis were obtained by pentacam anterior segment analysis system in 20 patients with normal eyes. SPSS17.0 software package was used to calculate the data. In myopia group, the diameter of pupil, central corneal thickness (CCT), the thinnest point corneal thickness (TCTT), anterior chamber volume (ACVV) and central anterior chamber depth (ACD) were higher than those before myopia. The results were statistically significant (P 0.05), horizontal axis curvature of anterior and posterior corneal surface was Rh, vertical axis curvature of anterior and posterior surface was Rvn, mean curvature of anterior and posterior corneal surface was Rm1, Q value of anterior and posterior corneal surface was Kappa angle X axis, anterior chamber angle ACAA, total high order aberration of cornea RMShs, cornea 3. There was no significant difference before and after mydriasis (P < 0.05. 2) in age-related cataract group: pupil diameter, thickness of the thinnest spot, anterior chamber volume, anterior chamber volume, central anterior chamber depth, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber, anterior chamber and anterior chamber. The ratio of Acas to the anterior mydriasis was larger than that before mydriasis. The results showed that there were significant differences in the central corneal thickness (CCT), the horizontal axis curvature of the anterior and posterior surface of the cornea, the vertical axis curvature of the anterior and posterior surface of the cornea, the mean curvature of the anterior and posterior surface of the cornea, the Q value of the anterior and posterior surface of the cornea, the Kappa angle X axis, the total high order aberration of the cornea RMSha. There was no significant difference before and after mydriasis (P < 0.05).) all subjects were: pupil diameter, central corneal thickness (CCT), thinnest point corneal thickness (TCTT), anterior chamber volume. ACVS, the depth of the central anterior chamber (ACD), the Kappa angle X axis, and the anterior chamber angle ACAA) were larger than those before mydriasis. The results were statistically significant (P 0.05); horizontal curvature of the anterior and posterior surface of cornea: Rhn; Vertical axis curvature of the anterior and posterior surfaces; mean curvature of the anterior and posterior surfaces; mean curvature of the anterior and posterior surfaces; Q value of the anterior and posterior surface of the cornea; total high order aberration of the cornea: RMShn; third order horizontal aberration of the cornea Z31C; cornea 3. There was no significant difference before and after mydriasis (P 0.05). Conclusion: normal eyes, normal eyes, normal eyes, normal eyes, normal eyes, no significant difference before and after mydriasis. In myopia group, pupil diameter, central corneal thickness and thinnest point corneal thickness increased, anterior chamber depth deepened, anterior chamber volume increased, pupil diameter, thinnest point corneal thickness and central anterior chamber depth deepened in cataract group. The volume of anterior chamber is increased. There is no obvious change in corneal curvature, corneal aberration and so on before and after pupil dilation. It is recommended that the examination be carried out under the condition of non-mydriasis; if the results of measurement under mydriasis really need to be used, it is recommended to make specific analysis in combination with clinical practice. The data which has no effect on the measurement parameters are selected for application.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R776.1

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