短波自发荧光、红外线及造影在评估视网膜色素上皮脱离病灶大小中的诊断价值

发布时间：2018-03-14 06:38

本文选题：自发荧光　切入点：红外线　出处：《广东医学》2017年03期 　论文类型：期刊论文

【摘要】：目的研究短波自发荧光(SW-AF)、红外线(IR)及眼底荧光血管造影(FFA)在评估视网膜色素上皮脱离(PED)病灶大小中的诊断价值。方法采用SPECTRALIS HRA共焦激光扫描检测镜的IR、AF模式,对37例(37眼)行光学相干断层扫描(OCT)、FFA、IR及SW-AF检查,评估IR、AF及FFA的影像学特征。结果PED基底部宽度分别与IR、SW-AF及FFA宽度比较,差异有统计学意义(t=-3.210,P=0.003;t=-3.432,P=0.002;t=-2.346,P=0.025)。其中,老年性黄斑变性引起的PED基底部宽度与IR、SW-AF宽度相比差异有统计学意义(t=-3.399,P=0.003;t=-3.094,P=0.007),与FFA宽度相比差异无统计学意义(t=-2.101,P=0.051)。中心性浆液性脉络膜视网膜病变引起的PED与IR、SW-AF及FFA宽度比较相比,差异无统计学意义(t=-2.131,P=0.059;t=-2.232,P=0.050;t=-1.511,P=0.162)。息肉状脉络膜血管病变引起的PED差异亦无统计学意义(t=-1.104,P=0.306;t=-1.960,P=0.091;t=-0.915,P=0.391)。相关性分析结果显示,老年性黄斑变性引起的PED基底部宽度及高度、IR、SW-AF和FFA宽度均与最佳矫正视力呈负相关,差异均有统计学意义(P0.05),中心性浆液性脉络膜视网膜病变引起的PED基底部宽度及高度、IR和FFA宽度均与最佳矫正视力呈负相关,差异均有统计学意义(P0.05),息肉状脉络膜血管病变引起的PED上述各项观察指标与最佳矫正视力均无相关性(P0.05)。结论在评估PED病灶大小方面,IR、SW-AF及FFA评估效果尚不确切,不能作为测量PED的补充方法。
[Abstract]:Objective to study the diagnostic value of short wave autofluorescence SW-AFN (IR) and fundus fluorescein angiography (FFA) in evaluating the lesion size of retinal pigment epithelium detachment (PED). Methods SPECTRALIS HRA confocal laser scanning was used to detect the pattern of SPECTRALIS. In 37 cases (37 eyes), the imaging features of PED were evaluated by optical coherence tomography (Oct) FFAF and SW-AF. Results the base width of PED was significantly different from that of IRT SW-AF and FFA respectively. There were significant differences between PED base base width and FFA width. There was a significant difference between PED base base width and FFA width, and the difference was statistically significant between 3. 432P0. 002p0. 002t and 0. 0250.The results showed that there was no significant difference between PED base base width and IRU SW-AF and FFA width. There were significant differences between PED base base width and IRU SW-AF and FFA width. The base width of PED caused by age-related macular degeneration was significantly different from that of IRN SW-AF. There was no significant difference between PED and IRSW-AF and the width of PED was compared with that of IRSW-AF and FFA in central serous chorioretinopathy. There was no significant difference in PED caused by polypoid chorioangiopathy. There was no significant difference in PED caused by polypoid choroidal angiopathy. The base width of PED and the width of IRI SW-AF and FFA caused by age-related macular degeneration were negatively correlated with the best corrected visual acuity (BCVA). The differences were statistically significant (P 0.05). The base width of PED, height of IR and FFA width of central serous chorioretinopathy were negatively correlated with the best corrected visual acuity (BCVA). All the differences were statistically significant (P 0.05). There was no correlation between the above observed indexes and the best corrected visual acuity (BCVA) of PED caused by polypoid choroidal vascular disease. Conclusion it is still not accurate to evaluate the size of PED lesions by IRI SW-AF and FFA. It cannot be used as a supplementary method for measuring PED.
【作者单位】：中南大学湘雅医学院附属海口医院眼科;
【基金】：海南省科学技术厅创新引进集成专项科技合作项目(编号:KJHZ2013-15)
【分类号】：R774.5

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