不同年龄段马凡综合征晶状体不全脱位患者角膜特征及意义

发布时间：2018-03-19 07:10

本文选题：马凡综合征　切入点：角膜曲率　出处：《眼科新进展》2017年11期 　论文类型：期刊论文

【摘要】：目的比较不同年龄段马凡综合征晶状体不全脱位患者的角膜特征并探讨其临床意义。方法马凡综合征组45例84眼和对照组84例84眼列入研究,前者按年龄分为两组:儿童组(5~14岁)49眼和非儿童组(14岁)35眼。使用Pentacam测量角膜曲率、角膜散光和中央角膜厚度。结果与对照组相比,马凡综合征组患者角膜变平、散光增大,两组间差异均具有统计学意义(均为P=0.000)。马凡综合征患者角膜前表面曲率儿童组为(40.02±1.42)D,非儿童组为(41.03±1.57)D;角膜后表面曲率儿童组为(-5.71±0.23)D,非儿童组为(-5.89±0.31)D;总角膜散光儿童组为(-1.71±0.84)D,非儿童组为(-1.34±0.78)D,两组相比差异均具有统计学意义(均为P0.05)。角膜前表面散光儿童组高于非儿童组(P=0.017),而后表面散光两组间差异无统计学意义(P=0.377)。儿童组总角膜散光和角膜前表面散光以顺规散光(69.39%)为主,而非儿童组顺规散光和斜向散光的比例相当。两组角膜后表面都以逆规散光为主(儿童组占85.71%,非儿童组占77.14%)。以角膜前表面散光估计总角膜散光时约有一半的患者会高估约0.32 D。结论马凡综合征晶状体不全脱位患者角膜变平、散光增大。儿童组角膜更扁平,总角膜散光和角膜前表面散光值较高,以顺规散光为主。马凡综合征患者的角膜后表面散光值较稳定,以逆规散光为主。忽视角膜后表面散光,以角膜前表面散光值估计总角膜散光时易高估。
[Abstract]:Objective to compare the corneal features and clinical significance of patients with Marfan syndrome with incomplete dislocation of lens in different age groups. Methods 45 cases (84 eyes) of Marfan syndrome group and 84 eyes of 84 cases (control group) were included in the study. Pentacam was used to measure corneal curvature, astigmatism and central corneal thickness. Results compared with the control group, the cornea flattened and astigmatism increased in the Marfan syndrome group. There were significant differences between the two groups (P < 0.000). The anterior surface curvature of cornea was 40.02 卤1.42D in children with Marfan syndrome, 41.03 卤1.57D in non-children, -5.71 卤0.23D in children with corneal posterior surface curvature, -5.89 卤0.31D in non-children, and -1.71 卤0.84D in children with total corneal astigmatism. The difference between the two groups was statistically significant (P 0.05). The anterior corneal surface astigmatism in children group was higher than that in non-children group (P 0.017), but there was no significant difference between the two groups in posterior surface astigmatism. The total corneal astigmatism and corneal astigmatism in children group were not significantly different. The main astigmatism of the front surface is in accordance with the rules of astigmatism (69.39). The proportion of normal astigmatism and oblique astigmatism was the same in non-children group. The posterior surface of cornea in both groups was mainly converse astigmatism (85.71 in children group, 77.14 in non-child group). About half of the patients estimated total corneal astigmatism by anterior corneal surface astigmatism. Conclusion the cornea flattened in patients with Marfan's syndrome with incomplete lens dislocation. The corneal astigmatism in the children group was more flat, the total corneal astigmatism and the corneal anterior surface astigmatism were higher, the main astigmatism was regular astigmatism. In the patients with Marfan's syndrome, the astigmatism value of the posterior surface of cornea was more stable, the main astigmatism was reverse astigmatism, and the corneal posterior surface astigmatism was ignored. It is easy to overestimate the total corneal astigmatism based on the corneal anterior surface astigmatism.
【作者单位】：复旦大学附属眼耳鼻喉科医院眼科;维吾尔族自治区喀什地区第二人民医院眼科;
【基金】：国家自然科学基金联合基金资助(编号:U1503124) 新疆维吾尔自治区自然科学基金资助(编号:2015211C225)~~
【分类号】：R776.2

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