角膜塑形镜控制青少年低中高度近视发展的效果

发布时间：2018-03-25 17:24

本文选题：角膜塑形镜　切入点：近视　出处：《中山大学学报(医学科学版)》2017年04期

【摘要】：【目的】探讨过夜配戴角膜塑形镜(OK镜)治疗青少年轻度、中度及高度近视的效果差异。【方法】前瞻性病例研究。收集54例(107眼)青少年近视患者,平均年龄(11.6±2.4)岁,按患者戴镜前等效球镜度分为低度近视组(51眼,-0.75~-3.00 D)、中度近视组(36眼,-3.25~-5.00 D)及高度近视组(20眼,-5.25~-9.00 D)。观察配戴前1天及配戴1年后3组内及组间等效球镜度、中央角膜厚度、角膜曲率、前房深度和眼轴变化。【结果】轻度近视组、中度近视组及高度近视组基线平均等效球镜度(D)分别为-2.15±0.63、-4.20±0.54和-6.63±1.18;三组基线眼轴(mm)分别为24.50±0.66、25.16±0.65及26.35±0.87。三组患者基线中央角膜厚度、前房深度、中央角膜K值、平K值及陡K值差异均无统计学意义。戴镜1年后3组眼轴增长值(mm)分别为0.22±0.27、0.09±0.22和0.02±0.22;其中低度近视组与中度近视组、高度近视组相比,组间眼轴增长值差异有统计学意义(P值分别为0.04、0.008),中度近视组与高度近视组两组间眼轴增长值差异无统计学意义(P值为0.35)。三组戴镜1年后等效球镜度显著下降,3组内差异均有统计学差异(P均0.0001),低度近视组与中度、高度近视组间差异具有统计学意义(P均0.0001)。1年前后3组中央角膜K值、平K值、陡K值均明显变平坦,组内差异比较均有统计学差异(P均0.0001)。中央角膜厚度、前房深度及角膜直径1年前后差异无统计学意义。【结论】中高度近视者采用角膜塑形镜控制近视的作用较低度近视更优。角膜曲率改变的量可能是影响OK镜近视治疗效果的主要因素之一。
[Abstract]:[objective] to explore the difference of effect of overnight wearing keratoplastic lens in the treatment of mild, moderate and high myopia in adolescents. [methods] A prospective case study was carried out in 54 patients with juvenile myopia (mean age 11.6 卤2.4 years). The patients were divided into low myopia group (51 eyes) and moderate myopia group (36 eyes) and high myopia group (20 eyes). [results] the baseline mean equivalent spherical lens (BCE) of mild myopia group, moderate myopia group and high myopia group were -2.15 卤0.63 卤0.54 and -6.63 卤1.18, respectively, and the baseline corneal thickness of the three groups were 24.50 卤0.6625.16 卤0.65 and 26.35 卤0.87.The mean mean mean BCET of the three groups was 24.50 卤0.6625.16 卤0.65 and 26.35 卤0.87respectively. There was no significant difference in anterior chamber depth, central corneal K value, flat K value and steep K value. After one year, the axial growth values of the three groups were 0.22 卤0.270.9 卤0.22 and 0.02 卤0.22, respectively, among which the low myopia group was compared with the moderate myopia group and the high myopic group. There was significant difference in the axial growth between the three groups (P = 0.04 0. 008), but there was no significant difference between the moderate myopia group and the high myopia group (P = 0. 35). There were statistical differences between the two groups (P = 0.0001, P = 0.0001, P = 0.0001, P = 0.0001, P = 0.0001). The central corneal K value, flat K value and steep K value of the three groups were significantly flattened before and after one year, and there were significant differences in the difference between the three groups (P = 0.0001, P = 0.0001, P = 0.0001, P = 0.0001, P = 0.0001, P = 0.0001, P = 0.0001, P = 0.0001, P < 0.01). There was no significant difference in anterior chamber depth and corneal diameter before and after one year. [conclusion] the effect of corneal plastic lens on myopia is better than that of low myopia. The change of corneal curvature may be the effect of OK lens myopia. One of the main factors of therapeutic effect.
【作者单位】：中山大学中山眼科中心//眼科学国家重点实验室;
【基金】：国家自然科学基金(81200716)
【分类号】：R778.11

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