CPAP治疗对阻塞性睡眠低通气综合征患者导管消融术后心房颤动复发率影响的Meta分析

发布时间：2018-03-26 10:39

本文选题：持续气道正压通气　切入点：阻塞性睡眠呼吸暂停低通气综合征　出处：《临床心血管病杂志》2017年05期

【摘要】：目的:系统评价持续气道正压通气(CPAP)对阻塞性睡眠低通气综合征(OSA)患者经导管消融术后心房颤动(AF)复发率的影响。方法:计算机检索PubMed、MEDILINE、EMBASE、Cochrane library、知网、万方等数据库,检索时限从建库到2016年10月。严格按照纳入和排除标准筛选文献并提取数据,评价纳入研究的质量后,采用Stata 14软件进行Meta分析。结果:共纳入6篇队列研究,共计1 044例OSA合并AF患者。Meta分析结果显示:CPAP治疗后OSA患者导管消融术后AF的复发率显著低于对照组(RR=0.68,95%CI:0.58~0.79,I2=0,P=0.911)。结论:CPAP治疗可有效降低OSA患者导管消融术后AF的复发率,提示临床医生在诊治OSA合并AF患者过程中可以考虑使用CPAP进行治疗。
[Abstract]:Objective: to systematically evaluate the effect of CPAP on the recurrence rate of atrial fibrillation (AF) in patients with obstructive sleep hypopnea syndrome (OSAs) after catheter ablation. The retrieval time was from the construction of the database to October 2016. The literature was screened according to the inclusion and exclusion criteria strictly and the data were extracted. After evaluating the quality of the inclusion study, Meta analysis was carried out with Stata 14 software. Results: six cohort studies were included. A total of 1 044 OSA patients with AF. Meta-analysis showed that the recurrence rate of AF in OSA patients after OSA was significantly lower than that in the control group. It suggests that clinicians may consider the use of CPAP in the diagnosis and treatment of OSA with AF.
【作者单位】：昆明理工大学信息工程与自动化学院昆明;云南省第一人民医院呼吸科;
【基金】：国家自然科学基金资助项目(No:61163021)
【分类号】：R541.75;R766

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