基于体素灰质不对称性方法的单侧突发感音神经性耳聋研究

发布时间：2018-03-28 00:38

本文选题：突发感音神经性耳聋　切入点：灰质不对称性　出处：《临床放射学杂志》2017年11期

【摘要】：目的通过基于体素的灰质不对称性系数(AI),研究单侧突发感音神经性耳聋患者大脑灰质结构的改变。方法搜集86例单侧突发感音神经性耳聋患者及105名听觉正常的健康志愿者(对照组)的高分辨磁共振结构像数据,采用基于体素形态分析法,计算大脑灰质体积AI,统计分析不同侧别突聋患者大脑灰质体积偏侧化程度的改变。结果与对照组相比,左侧突聋患者部分脑区存在左侧化及右侧化程度的改变,而右侧突聋患者只在部分脑区存在右侧化程度的改变。结论单侧突发感音神经性耳聋患者存在大脑灰质体积AI的改变,提示我们与突聋有关的体素水平大脑结构重组及灰质体积偏侧化程度的改变。
[Abstract]:Objective through the gray matter asymmetry coefficient based on voxel Research (AI), unilateral sudden sensorineural hearing loss in patients with brain gray matter structure changes. Methods 86 cases with unilateral sudden sensorineural hearing loss patients and 105 hearing normal healthy volunteers (control group) by high resolution magnetic resonance image data structure, using the method of analysis of voxel based morphometry, calculate the volume of gray matter in the brain AI, statistical analysis of different side in patients with sudden sensorineural hearing loss of brain gray matter volume laterality changes. Results compared with the control group, the left and right are the degree of change in patients with sudden deafness left brain region, while the right side in patients with sudden deafness only in some brain regions exist the degree of change. Conclusion unilateral sudden sensorineural hearing loss in patients with brain gray matter volume changes in AI, suggesting that we associated with sudden deafness voxel level brain structure and gray matter volume lateralization process A change in degree.

【作者单位】：华中科技大学同济医学院附属协和医院放射科;
【基金】：湖北省自然科学基金知识创新专项项目(编号:2017CFB796)
【分类号】：R445.2;R764.437

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