基于渐变的内耳早期发育三维仿真与测量

发布时间：2018-04-04 10:43

本文选题：内耳　切入点：三维仿真　出处：《浙江理工大学》2017年硕士论文

【摘要】：当今世界越来越多人被内耳疾病所困恼,内耳是听觉的功能性器官,深入研究内耳早期发育是探索治疗方法的重要途径。本文提出一种基于渐变的内耳早期发育三维仿真方法解决内耳发育的计算机仿真问题,另外通过对内耳发育阶段三维模型及其渐变过程中的模型进行测量,给出一些测量数据,为渐变过程提供有效信息。论文主要工作如下:(1)源模型和目标模型特征点对获取。通过石蜡切片和三维重建技术构建源模型和目标网格模型,计算模型网格显著度,设定相应阈值提取出模型显著特征点信息,该方法简单快捷并且具有良好的抗噪性。构造源模型和目标模型包围盒,通过轴向将两模型近似对齐,将目标网格模型上特征点投影到源网格模型上,投影点即为对应的特征点,从而获取模型间的特征点对信息。(2)应用三维渐变技术实现内耳早期发育仿真过程。将三维模型上提取出的特征点对信息作为约束条件,构建一个径向基函数插值的隐式曲面函数,通过求解构建出的线性方程组,得到隐式曲面函数,即模型间的映射函数,从而建立模型顶点之间的匹配映射关系。在获得源模型和目标模型间的对应关系的基础上,采用拉普拉斯坐标双线性插值的方法进行路径插值,实现三维渐变的过程。此外,通过加入网格优化算法和平滑策略解决网格模型渐变过程中三角面片尺寸过大、狭长和渐变平滑等问题。(3)内耳早期发育三维测量。通过构建包围盒获得源网格模型与目标网格模型以及渐变过程中模型的三维尺寸信息,同时利用三维网格面片等信息可以获得网格模型的体积、面积等。这些模型测量数据对于计算机仿真具有重要作用,同时为内耳早期发育的研究提供有效的数据信息。本文通过构建径向基函数插值的隐式曲面函数和路径插值算法实现对内耳早期发育的计算机可视化仿真,该算法实现简单快捷,渐变过程自然平滑,对内耳早期发育的可视化仿真达到较好的效果。
[Abstract]:Nowadays, more and more people in the world are annoyed by inner ear disease, which is the functional organ of hearing.In this paper, a 3D simulation method based on gradual change for the development of inner ear is proposed to solve the problem of computer simulation of the development of inner ear. In addition, by measuring the three-dimensional model of inner ear development stage and the model in the process of gradual change, some measuring data are given.Provides effective information for the gradient process.The main work of this paper is as follows: 1) Source model and target model feature point pair acquisition.The source model and target mesh model are constructed by paraffin slice and 3D reconstruction techniques. The mesh saliency of the model is calculated and the corresponding threshold is set to extract the model salient feature point information. The method is simple and fast and has good noise resistance.The bounding box of the source model and the target model is constructed, the two models are approximately aligned by axial alignment, and the feature points on the target mesh model are projected onto the source grid model. The projection points are the corresponding feature points.Thus, the feature pairs of the models are obtained. The 3D gradient technique is used to simulate the early development of the inner ear.Taking the feature pair information extracted from 3D model as the constraint condition, an implicit surface function with radial basis function interpolation is constructed. By solving the linear equation set, the implicit surface function, that is, the mapping function between models, is obtained.Thus the matching mapping relationship between vertices of the model is established.On the basis of obtaining the corresponding relation between the source model and the target model, the path interpolation method of Laplace coordinate bilinear interpolation is used to realize the process of 3D gradual change.In addition, the mesh optimization algorithm and smoothing strategy are added to solve the problems of too large triangulated surface size, narrow length and gradual smoothing in the process of mesh model gradient, etc.) the three-dimensional measurement of inner ear development in the early stage is solved.By constructing the bounding box, the 3D size information of the source mesh model, the target mesh model and the model in the process of gradual change can be obtained. At the same time, the volume and area of the mesh model can be obtained by using the information of the three-dimensional mesh surface.The data measured by these models are important for computer simulation and provide effective data information for the study of early development of inner ear.In this paper, the implicit surface function and path interpolation algorithm of radial basis function interpolation are constructed to realize the computer visual simulation of the early development of inner ear. The algorithm is simple and fast, and the process of gradual change is naturally smooth.Visual simulation of early development of inner ear achieves better results.
【学位授予单位】：浙江理工大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：TP391.41;R764

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