糖尿病性黄斑水肿激光治疗前后微视野变化研究

发布时间：2018-04-04 21:33

本文选题：糖尿病性黄斑水肿　切入点：MP-1微视野　出处：《广州中医药大学》2012年硕士论文

【摘要】：目的：评估激光治疗对糖尿病黄斑水肿患者视功能的影响。方法：对符合入选标准的23例40只眼糖尿病性视网膜病变患者行专科检查,眼底荧光血管造影了解水肿情况,在光凝前、光凝后3个月分别对患者进行光学相干断层扫描黄斑中心凹视网膜厚度,并采用MP-1微视野仪对相同患者行中心10。平均视网膜光敏度、固视稳定性(固视稳定或固视不稳定)、固视位置(中心固视或偏中心固视)检查。填写DME症状统计表及观察表,包括一般资料、全身症状、舌脉、国际标准视力表最佳矫正视力、激光治疗前、治疗后1个月及3个月各个阶段MP-1微视野情况等；最后将所有资料录入数据库,进行配对t检验、秩和检验及双变量相关进行统计与分析。结果： 23个患者40只眼,激光治疗后3个月视力、平均视网膜光敏度、固视稳定性、固视位置及黄斑厚度与激光治疗前差异有显著统计学意义；激光治疗前后视力、固视稳定性、固视位置及平均视网膜光敏度与黄斑厚度呈负相关,相关性有统计学意义；激光治疗前后视力与平均光敏感度呈正相关,相关性有统计学意义；激光治疗前后固视位置及平均光敏度与固视稳定性呈正相关,相关性有统计学意义；中医证型与激光前后视力无相关性。结论：资料显示,激光对糖尿病性黄斑水肿患者视力、黄斑厚度、视网膜光敏感度、固视稳定性、固视位置在治疗后3个月有明显改善作用。
[Abstract]:Objective:To evaluate the effect of laser therapy on visual function in diabetic macular edema patients.Methods:Twenty three patients (40 eyes) with diabetic retinopathy who met the inclusion criteria were examined by special examination, fundus fluorescein angiography (FFA) was performed to find out the edema, and before photocoagulation,The retinal thickness of macular central fovea was scanned by optical coherence tomography 3 months after photocoagulation, and the center of the same patient was measured by MP-1 microfield.The mean retinal Guang Min degree, fixation stability (fixed vision stability or fixed vision instability), fixed vision position (central fixation or partial central fixation) were examined.Filling out DME symptom statistics and observation forms, including general information, systemic symptoms, tongue vein, international standard visual acuity, MP-1 microvisual field of each stage before, 1 month and 3 months after laser treatment, etc.Finally, all the data are entered into the database and analyzed by paired t test, rank sum test and bivariate correlation.Results:The visual acuity, mean retinal Guang Min degree, fixation stability, fixation position and macular thickness of 23 eyes were significantly different from those before and after laser treatment.The position of fixed vision and the mean retinal Guang Min degree were negatively correlated with macular thickness, the visual acuity was positively correlated with mean light sensitivity before and after laser treatment, and the correlation was statistically significant.There was a positive correlation between the fixed vision position and the average Guang Min degree before and after laser treatment, and the correlation was statistically significant, while there was no correlation between the type of TCM syndrome and the visual acuity before and after laser treatment.Conclusion:The results showed that laser could significantly improve the visual acuity, macular thickness, retinal light sensitivity, fixation stability and fixation position of diabetic macular edema patients 3 months after treatment.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R587.2;R774.5

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