变应性鼻炎儿童的生活质量评价分析

发布时间：2018-04-08 17:03

本文选题：鼻炎　切入点：变应性　出处：《首都医科大学》2012年硕士论文

【摘要】：目的评价变应性鼻炎(allergic rhinitis, AR)儿童的生活质量以及对儿童鼻-结膜炎生活质量量表调查表( Pediatric Rhino-conjunctivitis Quality of Life Questionnaire,PRQLQ)中各项评价指标间的相关性进行分析。方法随机抽取2006年7月-2007年9月北京儿童医院耳鼻喉科对北京地区学龄前3-5岁儿童进行AR流行病学调查中确诊为AR儿童51例,男孩37例,女孩14例,年龄在8.00岁~11.17岁,平均年龄为(9.85±0.85)岁;同期的健康儿童52例,男孩27例,女孩25例,年龄在8.33岁~11.25岁,平均年龄为(9.94±0.71)岁。两组的年龄无统计学差异(t=0.54,P0.05)。再次电话随访,AR儿童再次行皮肤点刺试验(Skin Prick Test,SPT),用PRQLQ来评价AR儿童的生活质量的五方面及23项目,使用SPSS 13.0进行统计学分析。结果 1、AR儿童PRQLQ五方面评分的均值都明显高于对照组,统计学有显著性差异(P0.01)。 2、AR儿童PRQLQ五方面间及23项目间的比较差异有统计学意义(F=36.56,P0.01;F=14.71,P0.01)。鼻部症状是患儿生活质量受影响较明显的方面(2.52±1.27)。评分最高的项目依次为鼻塞、鼻痒、流涕、喷嚏(2.47±1.47; 2.55±1.45;2.53±1.42;2.55±1.47),四者间差异无统计学意义(P 0.05)。 3、相关性分析显示: 3.1鼻部症状和鼻炎相关行为问题显著相关(r=0.82,P0.01)。基金项目:北京市自然科学基金资助,项目编号:2009/3125 3.2鼻部症状和非鼻-结膜炎症状显著相关(r=0.74,P0.01)。鼻部症状和注意力难以集中显著相关(r=0.59,P0.01)。注意力难以集中和鼻痒、流涕呈正相关(r=0.58,P0.01;r=0.59,P0.01)。难以入睡和鼻痒症状显著相关(r=0.57,P0.01)。 3.3鼻部症状和情感反应显著相关(r=0.68,P0.01)。鼻部症状和尴尬显著相关(r=0.66,P0.01)。尴尬和鼻痒、流鼻涕显著相关(r=0.58,P0.01;r=0.66,P0.01)。 3.4鼻部症状和眼部症状显著相关(r=0.56,P0.01)。 3.5鼻炎相关行为问题和情感反应显著相关(r=0.74,P0.01)。尴尬和需携带面巾纸、需揉鼻或眼显著相关(r=0.65,P0.01;r=0.58,P0.01)。结论 1、AR儿童的生活质量较健康儿童受到更为明显的影响。 2、鼻部症状是儿童患者生活质量最受影响的方面。鼻塞、鼻痒、流涕、喷嚏是患儿最常见的症状。 3、相关性分析提示:鼻部症状可能是影响鼻炎相关行为问题、非鼻-结膜炎症状、情感反应的主要原因。鼻炎相关行为问题可能是导致情感反应的主要原因。
[Abstract]:PurposeMethodFrom July 2006 to September 2007, 51 children (37 boys and 14 girls) were diagnosed as AR by the otolaryngology department of Beijing Children's Hospital from July 2006 to September 2007. Their age was 8.00 years old or 11.17 years old.The mean age was 9.85 卤0.85 years, and 52 healthy children, 27 boys and 25 girls, aged from 8.33 years to 11.25 years, with an average age of 9.94 卤0.71 years.There was no significant difference in age between the two groups.The skin Prick test was used to evaluate the five aspects and 23 items of quality of life of AR children by PRQLQ. SPSS 13.0 was used for statistical analysis.Result1the mean PRQLQ score of children with AR was significantly higher than that of the control group (P 0.01).(2) there were significant differences between the five aspects of PRQLQ in children with AR and the differences among the 23 items. There was a significant difference between them (P = 36.56, P = 0.01F = 14.71, P = 0.01a, P = 0.01a, P = 0.01).Nasal symptoms were significantly affected by the quality of life of the children (2.52 卤1.27).The highest scores were nasal congestion, itching, runny nose, sneezing 2.47 卤1.47 and 2.55 卤1.45 ~ 2.53 卤1.42 ~ 2.55 卤1.47 respectively. There was no significant difference among the four groups (P 0.05).3. Correlation analysis shows that:3.1 there was a significant correlation between nasal symptoms and rhinitis related behavioral problems (P 0.01).Project: supported by Beijing Natural Science Foundation, Project No.: 2009 / 31253.2 there was a significant correlation between nasal symptoms and non-rhinoconjunctivitis symptoms (P 0.01).There was a significant correlation between nasal symptoms and attention.There was a positive correlation between nasal itching and distraction, and there was a positive correlation between the volume of rhizoid and the rhizoid concentration of 0.58% (P 0.01) and 0.59% (P 0.01).There was a significant correlation between the difficulty of falling asleep and the symptoms of nasal itching.3.3 there was a significant correlation between nasal symptoms and emotional responses.Nasal symptoms were significantly correlated with embarrassment (P 0.01).Embarrassed and itchy nose, runny nose was significantly correlated with 0.58% P 0.01 ~ 0.66% ~ 0.66% P _ (0.01) ~ 0. 01%.3.4 there was a significant correlation between nasal symptoms and ocular symptoms.3.5 there was a significant correlation between rhinitis related behavioral problems and affective responses (P 0.01).Embarrassment and need to carry face napkin, need to rub nose or eyes significantly related to 0.65% P0.01A 0.58% P0.01C.ConclusionThe quality of life of AR children was significantly affected than that of healthy children.2. Nasal symptoms are the most affected aspect of children's quality of life.Stuffiness, itching, runny nose and sneezing are the most common symptoms in children.3, correlation analysis suggests that nasal symptoms may be the main cause of affecting rhinitis related behavioral problems, non-nasopharyngeal conjunctivitis symptoms and emotional reactions.Rhinitis-related behavioral problems may be the main cause of emotional response.
【学位授予单位】：首都医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R765.21

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