脑梗死合并OSAHS患者脑血管储备能力的相关研究

发布时间：2018-04-13 01:18

本文选题：脑梗死 + 阻塞性睡眠呼吸暂停低通气综合征　；参考：《重庆医学》2017年33期

【摘要】：目的探讨脑梗死合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者脑血管储备能力。方法 2014年6月至2016年4月该院收治的76例脑梗死合并OSAHS患者为A组,76例脑梗死患者为B组,同时期的76例健康体验人群为C组。检测3组研究对象呼吸暂停低通气指数(AHI)和夜间最低血氧饱和度(LSaO2)、平静呼吸呼气末二氧化碳分压(ETCO2)、低碳酸血症时ETCO2、高碳酸血症时ETCO2,低碳酸血症、高碳酸血症时脑血管储备能力等指标。结果 3组研究对象AHI、LSaO2、脑血管储备值比较,差异有统计学意义(P0.05),A组不同OSAHS严重程度患者差异有统计学意义(P0.05);平静呼吸ETCO2、低碳酸血症时ETCO2、高碳酸血症时ETCO2比较,差异均无统计学意义(P0.05),A组不同OSAHS严重程度患者差异均无统计学意义(P0.05)。低碳酸血症、高碳酸血症时,脑梗死合并OSAHS患者脑血管储备值与AHI呈负相关(P0.05),与LSaO2呈正相关(P0.05)。结论脑梗死合并OSAHS患者脑血管储备能力与患者病情程度有关。
[Abstract]:Objective to investigate the cerebrovascular reserve capacity of patients with cerebral infarction complicated with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods from June 2014 to April 2016, 76 patients with cerebral infarction complicated with OSAHS in our hospital were divided into group A (n = 76), group B (n = 76) and group C (n = 76).The apnea hypopnea index (AHII) and nocturnal minimum oxygen saturation (LSAO _ 2) were measured in three groups.Cerebral vascular reserve ability in hypercapnia.Results there were significant differences in AHIL SaO2 and cerebrovascular reserve value among three groups. There were significant differences in patients with different severity of OSAHS in group A (P 0.05), in patients with low carbon acidemia and in patients with hypercapnia, there were significant differences in patients with different severity of OSAHS (P 0.05), and in patients with low carbon acidemia and hypercapnia, there was a significant difference in ETCO2 between the three groups.No significant difference was found in all patients with different OSAHS severity in group A (P 0.05).In the case of hypocapnia and hypercapnia, the cerebrovascular reserve value in patients with cerebral infarction complicated with OSAHS was negatively correlated with AHI (P 0.05) and positively correlated with LSaO2 (P 0.05).Conclusion the cerebrovascular reserve ability in patients with cerebral infarction complicated with OSAHS is related to the severity of the disease.
【作者单位】：海南省海口市人民医院神经内科;海南省海口市人民医院肿瘤化疗科;
【基金】：海南省卫生厅立项项目(1401320-54A2004)
【分类号】：R743.33;R766

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