鼻用纤维素粉末治疗变应性鼻炎的临床疗效研究

发布时间：2018-04-25 22:25

本文选题：鼻用纤维素粉末 + 鼻炎　；参考：《临床耳鼻咽喉头颈外科杂志》2017年02期

【摘要】：目的:探讨鼻用纤维素粉末治疗变应性鼻炎的临床疗效。方法:将50例变应性鼻炎患者随机分成实验组和对照组,每组各25例(最终分别完成24例及25例)。实验组鼻腔局部使用鼻用纤维性粉末喷鼻,对照组使用生理性海水喷鼻,于治疗3个月后评价患者鼻气道阻力、鼻部症状评分、鼻结膜炎生存质量量表(RQLQ)、嗅觉功能、鼻黏膜纤毛清除功能及不良反应。结果:2组患者均未见明显不良反应。实验组治疗后鼻阻力、鼻部症状评分及RQLQ评分(眼部症状除外)均较治疗前显著改善,其鼻部症状中的鼻痒、流涕、喷嚏症状及RQLQ中的睡眠、非鼻症状、鼻部症状、情感改善情况显著优于对照组,差异有统计学意义(P0.05);而2组患者治疗后嗅觉功能及鼻黏膜纤毛清除功能均未见明显改善(P0.05)。结论:鼻用纤维素粉末使用安全,可显著改善变应性鼻炎患者的主观症状,提高其生活质量。
[Abstract]:Objective: to investigate the clinical effect of nasal cellulose powder in the treatment of allergic rhinitis. Methods: 50 cases of allergic rhinitis were randomly divided into experimental group and control group with 25 cases in each group (24 cases and 25 cases respectively). The nasal cavity of the experimental group was locally sprayed with fibrous powder, while the control group was treated with physiologic seawater. After 3 months of treatment, the nasal airway resistance, nasal symptom score, rhinoconjunctivitis quality of life scale (RQLQN), olfactory function were evaluated. Nasal mucosal cilia clearance function and adverse reactions. Results there were no obvious adverse reactions in the two groups. After treatment, nasal resistance, nasal symptom score and RQLQ score (except for ocular symptoms) were significantly improved in the experimental group. Nasal itch, runny, sneezing and RQLQ sleep, non-nasal symptoms, and nasal symptoms were found in the experimental group. The affective improvement was significantly better than that in the control group (P 0.05), but the olfactory function and nasal mucosal cilia clearance function were not significantly improved in the two groups after treatment. Conclusion: the use of nasal cellulose powder is safe, can significantly improve the subjective symptoms of allergic rhinitis patients and improve their quality of life.
【作者单位】：南京医科大学附属淮安第一医院耳鼻咽喉科;
【分类号】：R765.21

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