儿童非镇静听性脑干电反应的临床应用研究

发布时间：2018-05-02 05:59

本文选题：听性脑干电反应 + 非镇静　；参考：《昆明医科大学》2017年硕士论文

【摘要】：[目的]比较0～6岁儿童非镇静听性脑干电反应(Un-sedated auditory brainstem response,ABR)与传统镇静听性脑干电反应的反应阈及波V潜伏期,评价非镇静ABR在0～6岁儿童听力评估中的意义,以及比较0～6岁不同年龄段听力正常儿童非镇静ABR的V波潜伏期,进一步探讨非镇静ABR波V潜伏期的变化规律。[方法]将110例(220耳)0～6岁儿童根据年龄分为A(0～1岁)、B(1～3岁)、C(3～6岁)三组,其中A组38例(76耳),B组36例(72耳),C组36例(72耳),分别进行非镇静ABR及镇静ABR测试。比较所有测试者非镇静ABR与镇静ABR反应阈及波V潜伏期的相关性。同时,比较不同年龄段听力正常儿童,每组各20例(40耳),非镇静ABR波V潜伏期的差异。[结果]斯皮尔曼秩相关系数(Spearman's rho法)分析显示非镇静ABR与镇静ABR反应阈值显著相关(r=0.917,P0.01),非镇静ABR与镇静ABR波V潜伏期显著相关(r=0.888,P＜0.01);秩和检验(Wilcoxon讯号等级)分析显示非镇静ABR与镇静ABR反应阈值差异无统计学意义(Z=-0.674,P=0.500),非镇静ABR与镇静ABR波V潜伏期差异无统计学意义(Z=-2.438,P=0.15);Wilcoxon讯号等级分析显示不同年龄组听力正常儿童非镇静ABR波V潜伏期A(0～1岁)与B(1～3岁)差异有统计学意义(Z=-3.496,P0.05);A(0～1岁)与C(3～6岁)差异有统计学意义(Z=-3.982,P0.05),B(1～3岁)与C(3～6岁)差异无统计学意义(Z=-1.027,P=0.304)。[结论]儿童非镇静ABR与镇静ABR反应阈及V波潜伏期有良好的相关性,非镇静ABR技术可以有效的应用于儿童听性脑干电反应检测,该技术适用于不适合使用镇静类药物或不愿接受镇静的儿童受试者。
[Abstract]:[objective] to compare the threshold and V latency of unsedated auditory brainstem response and conventional sedation auditory brainstem response in children aged 0 to 6 years old, and to evaluate the significance of non-sedative ABR in hearing assessment of children aged 0 to 6 years old. The V wave latencies of non sedative ABR were compared between 0 and 6 years old children with normal hearing, and the changes of V latency of non sedation ABR waves were further discussed. [methods] 110 children aged 6 years old were divided into three groups: group A (38 cases, 76 ears), group B (36 cases, 72 ears), group C (36 cases, n = 72) were divided into three groups. The nonsedative ABR and sedative ABR test were performed respectively. The correlation between non-sedative ABR and sedation ABR reaction threshold and wave V latency was compared in all subjects. At the same time, the differences of V latency of non sedation ABR wave in 20 cases with 40 ears of normal hearing in each group were compared. [results] the Spelman rank correlation coefficient and Spearman's rho analysis showed that there was a significant correlation between non-sedative ABR and sedation ABR reaction threshold, and a significant correlation between non-sedative ABR and sedative ABR wave V latency (P < 0.01; rank sum test and Wilcoxon signal grade). There was no significant difference in the response threshold between non-sedative ABR and sedative ABR. There was no significant difference in V latency between non-sedative ABR and sedation ABR. There was significant difference between the age of 1 year (1 year) and the age of 1 year (3 years old). There was no significant difference between the two groups (ZHU -3.496P0.05P0.05P0.05P0.05- 1) and C3- (3-year-old) and C36-year-old) there was no significant difference between the two groups (P = 0.3040.304g / d, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304n = 0.304N). [conclusion] there is a good correlation between nonsedative ABR and ABR response threshold and V wave latency in children. Non-sedative ABR technique can be used to detect auditory brainstem response in children. This technique is suitable for children who are unsuitable for sedation or unwilling to accept sedation.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R764

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