玉屏风散加减辅助治疗过敏性鼻炎的系统评价

发布时间：2018-05-02 09:47

本文选题：玉屏风散 + 过敏性鼻炎　；参考：《中国药房》2017年21期

【摘要】：目的:系统评价玉屏风散加减辅助治疗过敏性鼻炎的疗效和安全性,为临床提供循证参考。方法:计算机检索万方数据库、中文科技期刊数据库、相关期刊论文、中国生物医学文献数据库、Cochrane图书馆、EMBase、Pub Med,收集玉屏风散加减联合化学药(试验组)对比单纯化学药(对照组)治疗过敏性鼻炎的随机对照试验,提取资料并按照Cochrane系统评价员手册5.1.0评价纳入研究质量,采用Rev Man 5.2统计软件进行Meta分析。结果:共纳入15项RCT,合计1 366例患者。Meta分析结果显示,试验组患者总有效率[OR=3.95,95%CI(2.80,5.58),P0.001]显著高于对照组,复发率[OR=0.37,95%CI(0.22,0.63),P0.001]和不良反应发生率[OR=0.15,95%CI(0.06,0.35),P0.001]显著低于对照组,差异均有统计学意义。结论:玉屏风散加减辅助治疗过敏性鼻炎疗效较好,可以降低复发率,安全性亦较好。
[Abstract]:Objective: to systematically evaluate the efficacy and safety of Yuping wind dispersion plus subtraction in the treatment of allergic rhinitis, and to provide evidence-based reference for clinical practice. Methods: computer retrieval of Wanfang database, Chinese sci-tech journal database, Chinese journal full text database, Chinese biomedical literature database, Cochrane library, EMBase, Pub Med, collection and subtraction of Yuping wind and subtraction. The combined chemical medicine (test group) was compared with the randomized controlled trial of the simple chemical (control group) treatment for allergic rhinitis. The data were extracted and the quality of the study was evaluated according to the Cochrane system evaluator's manual 5.1.0. The Meta analysis was carried out by the Rev Man 5.2 statistical software. Results: the results were included in 15 RCT, and the results of.Meta analysis in 1366 cases of the total of 1366 patients showed the test. The total effective rate of the patients was [OR=3.95,95%CI (2.80,5.58), and P0.001] was significantly higher than the control group. The recurrence rate was [OR=0.37,95%CI (0.22,0.63), P0.001] and the incidence of adverse reaction [OR=0.15,95%CI (0.06,0.35). P0.001] was significantly lower than that of the control group. The difference was statistically significant. Conclusion: Yuping wind dispersion plus subtraction for allergic rhinitis is better. It is also safe to reduce the recurrence rate.

【作者单位】：广州中医药大学第四临床医学院;广州中医药大学第一临床医学院;
【基金】：国家自然科学基金资助项目(No.81373567)
【分类号】：R765.21

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