急性青光眼与慢性青光眼患者睡眠质量的比较

发布时间：2018-05-02 12:36

本文选题：原发性急性闭角型青光眼 + 原发性慢性闭角型青光眼　；参考：《重庆医科大学》2017年硕士论文

【摘要】：目的:比较原发性急性闭角型青光眼(Primary acute angle-closure glaucoma,PAACG)、原发性慢性闭角型青光眼(Primary chronic angle-closure glaucoma,PCACG)患者与正常人群的睡眠质量。方法:选择2016年4月至2016年12月在重庆医科大学附属第二医院眼科病房住院的PAACG患者20例(急性组)、PCACG患者15例(慢性组),以同期在我院体检中心体检的24人(正常组)为观察对象。采用匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)对患者的睡眠质量进行测评。PSQI由24个评分条目组成,自评条目有19个,他评条目有5个。其中第19个条目和5个他评条目不参与计分,剩余的18个自评条目组成7个成份参与计分,每个成份有0~3个等级,分别对应0~3分,7个成份的累积得分即为PSQI总分,PSQI总分最高为21分。PSQI总分越高,表示睡眠质量越差,总分高于7分则认为存在睡眠障碍。由一个医师使用统一的指导语,按量表评定要求进行指导,被测试者独立完成问卷。问卷采用无记名的方式,当场收回。计量资料采用独立样本t检验或者秩和检验进行分析,计数资料采用卡方检验进行分析。结果:20例PAACG患者、15例PCACG患者和24例正常人均独立完成测试,全部纳入结果分析。(1)基本信息:急性组女性较男性多,慢性组和正常组患者则没有明显的性别差异;急性组年龄在50-85岁之间,平均年龄71.15±9.09岁,慢性组年龄在51-89岁之间,平均年龄66.20±12.73岁,正常组年龄在22-85岁之间,平均年龄67.88±6.44岁。(2)睡眠质量:急性组患者PSQI总分非常显著高于正常组(P0.05),且显著高于慢性组(P0.05),慢性组患者PSQI总分也显著高于正常组(P0.05);急性组与慢性组睡眠障碍者患病率(Percentage of patients with sleep disorders,PPSD)较正常组高(P0.05);急性组与慢性组PPSD之间差异没有统计学意义(P0.05)。(3)慢性组不同视野缺损程度患者PPSD的比较:慢性组患者按视野缺损程度分组后,各亚组间PPSD没有统计学意义(P0.05)。结论:PAACG和PCACG患者的睡眠质量较健康对照组差;PAACG和PCACG患者的PPSD较健康对照组高;PCACG患者的PPSD与视野缺损程度不存在相关性。
[Abstract]:Objective: to compare the sleep quality of primary acute angle-closure glaucoma primary chronic angle-closure glaucoma PCACGG patients with primary acute angle closure glaucoma (ACG) and normal subjects. Methods: from April 2016 to December 2016, 20 PAACG patients (15 cases of acute group) in the second affiliated Hospital of Chongqing Medical University were selected. Normal group) is the object of observation. The Pittsburgh sleep quality index (PSQI) was used to evaluate the sleep quality of the patients. PSQI was composed of 24 scoring items, 19 self-rating items and 5 other rating items. The 19th item and 5 other item are not included in the score, and the remaining 18 self-assessment items are composed of 7 components, each of which has 0-3 grades. The cumulative score of the seven components is that the highest total score of PSQI is 21. The higher the total score of PSQI is, the worse the sleep quality is, and the higher the total score is, the more the total score is, the higher the total score is. The questionnaire was completed independently by a physician who used a uniform guidance language and conducted the questionnaire according to the requirements of the scale. The questionnaire was collected on the spot by secret ballot. The measurement data were analyzed by independent sample t test or rank sum test, and the counting data were analyzed by chi-square test. Results 15 cases of PCACG and 24 cases of normal controls completed the test independently in 20 cases of PAACG. All of them were included in the analysis of results. The basic information was as follows: there were more women than men in acute group, but there was no significant gender difference between chronic group and normal group. The age of acute group was 50-85 years old, the average age was 71.15 卤9.09 years old, the age of chronic group was 51-89 years old, the average age was 66.20 卤12.73 years old, and that of normal group was 22-85 years old. Mean age 67.88 卤6.44 yrs) Sleep quality: the total score of PSQI in the acute group was significantly higher than that in the normal group, and significantly higher than that in the chronic group, and the total score of PSQI in the chronic group was significantly higher than that in the normal group, and the total score of PSQI in the acute group and the chronic group was significantly higher than that in the normal group. There was no significant difference in PPSD between acute group and chronic group. The comparison of PPSD in patients with different degree of visual field defect in chronic group: after grouping according to the degree of visual field defect in chronic group, there was no significant difference in PPSD between acute group and chronic group. There was no significant difference in PPSD between subgroups (P 0.05). Conclusion there is no correlation between PPSD and visual field defect in the patients with PCACG and the patients with PCACG. The sleep quality of the patients with PCACG is lower than that of the patients with PAACG and PCACG in the healthy control group, and the PPSD of the patients with PCACG is higher than that of the patients with PCACG in the healthy control group.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R775

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