自体血清联合泪道栓塞治疗干眼的疗效分析

发布时间：2018-05-05 12:42

本文选题：干眼 + 泪道栓塞术　；参考：《重庆医科大学》2015年硕士论文

【摘要】：目的：本文旨在探讨自体血清联合泪道栓塞治疗干眼与单纯自体血清治疗干眼的疗效比较。方法：选取2013年1月至2015年2月重庆医科大学附属第一医院眼科确诊为干眼症并住院治疗的54例(108眼),年龄在22-74岁之间的患者。按照治疗方法随意将其分为两组,采用自体血清联合泪道栓塞治疗的患者为A组(共26例,52只眼)其中男性6例,女性20例。单纯使用自体血清治疗的患者为B组(共28例,56只眼)其中男性9例,女性19例。分别治疗2周后,对A、B两组的疗效进行观察。包括角膜荧光素染色(CFS),泪膜破裂时间测定(BUT)、基础泪液分泌试验(SIt)检查,并对观察所得到的数据进行统计学分析。结果：2周后,A组、B组患者经治疗后,各项指标均有好转,且A组好转较为明显,两组疗效差异具有统计学意义(P0.05)。结论：自体血清联合泪道栓塞治疗干眼疗效高于单纯使用自体血清治疗,尤其对于重症干眼患者疗效显著。
[Abstract]:Objective: to compare the therapeutic effect of autologous serum combined with lacrimal duct embolization on dry eye and autologous serum alone. Methods: from January 2013 to February 2015, 54 patients with xerophthalmia diagnosed and hospitalized in the first affiliated Hospital of Chongqing Medical University, aged 22-74 years, were selected. According to the treatment method, they were randomly divided into two groups. The patients treated with autologous serum combined with lacrimal duct embolization were group A (26 cases with 52 eyes), including 6 males and 20 females. The patients treated with autologous serum alone were group B (28 patients with 56 eyes), including 9 males and 19 females. After 2 weeks of treatment, the curative effect of the two groups was observed. The results included corneal fluorescein staining (CFS), lacrimal film rupture time determination (BUTT), basic tear secretion test (SIt), and statistical analysis of the observed data. Results after 2 weeks of treatment, all the indexes of group A were improved, and the improvement of group A was obvious. The difference between the two groups was statistically significant (P 0.05). Conclusion: autologous serum combined with lacrimal duct embolization is more effective than autologous serum alone in the treatment of dry eye, especially in severe dry eye.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R777.34

【相似文献】