EDI-OCT在视网膜分支静脉阻塞患者筛板厚度测量中的应用

发布时间：2018-05-08 23:11

本文选题：青光眼 + 视网膜分支静脉阻塞　；参考：《眼科新进展》2017年05期

【摘要】：目的分析增强深部成像光学相干断层扫描(enhanced depth imaging optical coherence tomography,EDI-OCT)在测量视网膜分支静脉阻塞(branch retinal vein occlusion,BRVO)患者筛板厚度(lamina cribrosa thickness,LCT)中的应用价值。方法收集2014年9月至2016年3月我院收治的65例单侧BRVO患者的临床资料作为观察组,选取同期来我院体检的40位正常人的单眼健康眼作为对照组,采用EDI-OCT测量两组全周视网膜神经纤维层(retinal nerve fiber layer,RNFL)厚度、LCT、中央角膜厚度、眼轴长度、视盘横径、视盘竖径、屈光度、视野缺损范围等指标的变化。结果两组中央角膜厚度、眼轴长度、视盘横径、视盘竖径、屈光度比较差异均无统计学意义(均为P0.05);观察组视盘各区域LCT、全周RNFL厚度均低于对照组,差异均有统计学意义(均为P0.05);观察组视野缺损范围高于对照组(P0.05)。LCT与BRVO患者全周RNFL厚度呈正相关,与视野缺损呈负相关(P0.05)。结论 EDI-OCT可作为活体LCT检测的有效手段,青光眼BRVO患者LCT较正常健康人薄,且其LCT与全周RNFL厚度呈正相关,与视野缺损呈负相关。
[Abstract]:Objective to evaluate the value of enhanced depth imaging optical coherence tomography (EDI-OCTs) in the measurement of lamina cribrosa thicknessLCTs in patients with branch retinal vein occlusion (branch retinal vein occlusion BRV). Methods\ Methods the clinical data of 65 patients with unilateral BRVO from September 2014 to March 2016 in our hospital were collected as observation group, and 40 healthy eyes were selected as control group. The thickness of central cornea, length of eye axis, transverse diameter of optic disc, vertical diameter of optic disc, diopter and visual field defect were measured by EDI-OCT. Results there was no significant difference in central corneal thickness, axial length, transverse diameter of optic disc, vertical diameter of optic disc and diopter between the two groups (all P 0.05), the thickness of RNFL in all regions of the optic disc in the observation group was lower than that in the control group. The range of visual field defect in the observation group was higher than that in the control group (P 0.05). LCT was positively correlated with the thickness of RNFL in the whole cycle of BRVO, and negatively correlated with the visual field defect (P 0.05). Conclusion EDI-OCT can be used as an effective method for the detection of LCT in vivo. LCT in BRVO patients with glaucoma is thinner than that in normal controls, and its LCT is positively correlated with the thickness of RNFL and negatively correlated with visual field defect.
【作者单位】：潍坊医学院附属医院眼科;
【基金】：山东省自然科学基金资助(编号:ZR2013HL067)~~
【分类号】：R774.1

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