三维有限元模型分析OSAHS患者下颌不同前伸位置舌体变化的研究

发布时间：2018-05-12 06:08

本文选题：阻塞性睡眠呼吸暂停低通气综合征 + 三维有限元法　；参考：《宁夏医科大学》2012年硕士论文

【摘要】：目的建立阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者的上气道及毗邻结构的三维有限元模型，通过下颌逐步前伸，观察OSAHS患者舌体及舌后气道的形态学改变，为OSAHS的口腔矫治器治疗提供依据。方法对OSAHS患者上气道行薄层CT扫描，获得OSAHS患者上气道DICOM格式的图像信息，采用Mimics三维建模软件、Imageware逆向工程学软件、Ansys有限元分析软件建立上气道及毗邻结构的三维有限元模型，然后通过加载下颌骨逐步前伸，观察OSAHS患者舌体及舌后气道的形态变化及规律。结果建立了OSAHS患者上气道及毗邻结构的三维有限元模型，单元类型采用10节点的Solid92四面体单元。划分网格后，骨密质、骨松质、肌肉和气道各得到的单元数和节点数分别为：562920、50141、336789个单元，544929、84869、303134个节点。通过下颌骨前伸，舌体及舌后气道相应发生形态变化，其主要表现为：舌体前移，舌后气道平面其矢状径增大，横径相对减小，增加量大于减小量。结论应用螺旋CT技术和联合使用Mimics三维建模软件，Imageware软件，Ansys有限元分析软件建立OSAHS患者上气道及毗邻结构的三维有限元模型，证实通过CT可建立准确、可作灵活模拟操作的OSAHS患者上气道及其周围结构三维有限元模型，其建模效率高、速度快，模型的几何相似性较好，使用灵活；通过对有限元模型的下颌进行不同前伸位置的加载，有效打开舌后气道。证实了有限元分析方法的有效性，，为下颌前伸矫治器治疗OSAHS提供理论依据，同时为后续研究OSAHS患者上气道生物力学分析打下良好的基础。
[Abstract]:Objective to establish a three-dimensional finite element model of upper airway and adjacent structure in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). To provide the basis for oral appliance therapy of OSAHS. Methods the upper airway of OSAHS patients was scanned by thin slice CT, and the DICOM image of the upper airway of OSAHS patients was obtained. The 3D finite element model of upper airway and adjacent structure was established by using Mimics 3D modeling software / imageware reverse engineering software / Ansys finite element analysis software. Then, the morphology and regularity of tongue body and retrolingual airway of OSAHS patients were observed by mandibular extension. Results the 3D finite element model of upper airway and adjacent structure of OSAHS patients was established. The element type was 10 node Solid92 tetrahedron element. After meshing, the number of units and nodes in dense bone, cancellous bone, muscle and airway were 5449292984869 and 303134 nodes, respectively. According to the morphological changes of mandibular anterior extension, tongue body and retrolingual airway, the main features were as follows: the lingual body moved forward, the sagittal diameter of the retrolingual airway increased, the transverse diameter decreased, and the increment was greater than the decrease. Conclusion the 3D finite element model of upper airway and adjacent structure of patients with OSAHS can be established by using spiral CT and Mimics software imageware. It is proved that CT can be used to establish accurate 3D finite element model of upper airway and adjacent structure of patients with OSAHS. The 3D finite element model of upper airway and its surrounding structure of OSAHS patients, which can be simulated flexibly, has the advantages of high efficiency, high speed, good geometric similarity and flexible use. The postlingual airway was effectively opened by loading the mandible of finite element model at different protruding positions. It is proved that the finite element analysis method is effective, which provides a theoretical basis for the treatment of OSAHS with mandibular protruding appliance, and provides a good basis for further study on biomechanical analysis of upper airway in patients with OSAHS.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R766

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