STOP问卷在筛查阻塞性睡眠呼吸暂停中的应用

发布时间：2018-05-21 08:45

本文选题：阻塞性睡眠呼吸暂停综合征 + STOP问卷　；参考：《电子科技大学》2012年硕士论文

【摘要】：本研究的目的在于评估对于中国被试者使用STOP问卷筛查阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)的准确性，试图寻找一种更适合我国国情的简易筛选OSA的有效方法。通过比较华西医院睡眠医学中心400例门诊病人的STOP问卷和PSG检查结果，计算STOP问卷的敏感性及特异性，并与Berlin问卷的敏感性与特异性进行比较，以评估其使用的准确性，并尝试建立STOP问卷得分与睡眠呼吸暂停低通气指数（apnea-hypopnea index，AHI）的一元线性方程；同时对睡眠实验室的患者一般情况与睡眠呼吸状况进行初步的描述性研究与分析。以PSG为金标准，计算STOP问卷的敏感性、特异性分别为82.5%、72.4%；通过STOP问卷得分预测AHI的一元线性方程为，总体：Y=12.87X+1.64(X为stop得分，y为AHI指数)，男性：Y=11.39X+8.58，女性：Y=10.14X-1.45；四川大学华西医院睡眠医学中心睡眠障碍门诊患者中总的OSA患病率为75.5%，男性OSA患病率为85.8%，女性OSA患病率为53.5%。OSA患者深睡眠减少，浅睡眠增多。研究表明，STOP问卷对中国被试者筛查OSA具有较高的敏感性及适宜的特异性，，可以作为高度怀疑患有OSA的人群进行初筛诊断，其敏感性高于临床常用Berlin问卷的敏感性，因其简明易用值得推广。
[Abstract]:The purpose of this study was to evaluate the accuracy of using STOP questionnaire to screen obstructive sleep apnea (OSA) for Chinese subjects, and to find a simple and effective method for screening OSA in China. The sensitivity and specificity of STOP questionnaire were calculated by comparing the results of STOP questionnaire and PSG examination of 400 outpatients in sleep medicine center of West China Hospital. The sensitivity and specificity of STOP questionnaire were compared with that of Berlin questionnaire to evaluate the accuracy of its use. A linear equation between the scores of STOP questionnaire and apnea hypopnea index (AHII) was established, and the general situation and sleep breathing status of patients in sleep laboratory were studied and analyzed. Using PSG as the gold standard, the sensitivity of the STOP questionnaire was calculated, the specificity was 82.5 and 72.4, and the linear equation of predicting AHI by the score of the STOP questionnaire was: The total OSA prevalence rate of male was 75.5, that of male OSA was 85.8, that of female 53.5%.OSA was decreased, that of male was 11.39X 8.58, that of female was 10.14X-1.45.The total OSA prevalence rate was 75.5, the prevalence of male OSA was 85.8, and that of female OSA was lower than that of 53.5%.OSA, and the total OSA prevalence was 75.5in the outpatients of sleep disorder in the sleep medicine center of Huaxi Hospital of Sichuan University, and the prevalence rate of OSA in male was 85.8, and the prevalence of OSA in female was lower than that in 53.5%.OSA. Increased shallow sleep. The results show that stop questionnaire has a high sensitivity and a suitable specificity for screening OSA in Chinese subjects. It can be used as a preliminary screening diagnosis for people with highly suspected OSA, and its sensitivity is higher than that of Berlin questionnaire commonly used in clinical practice. It is worth popularizing for its simplicity and ease of use.
【学位授予单位】：电子科技大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：B841;R766

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