咽侧壁分层缝合联合软腭低温等离子消融治疗重度阻塞性睡眠呼吸暂停低通气综合征患者的疗效

发布时间：2018-05-25 21:00

本文选题：阻塞性睡眠呼吸暂停低通气综合征 + 软腭　；参考：《吉林大学学报(医学版)》2017年03期

【摘要】：目的:探索咽侧壁分层缝合(SSLPW)联合软腭低温等离子消融治疗重度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的可行性和临床效果。方法:收集行咽侧壁成形术(LP)联合软腭低温等离子消融术治疗的21例重度OSAHS患者(LP组)和行SSLPW联合软腭低温等离子消融术治疗的39例重度OSAHS患者(SSLPW组)的临床资料,回顾性分析2组患者术前和术后呼吸暂停低通气指数(AHI)、最低动脉血氧饱和度(LSaO_2)、Epworth嗜睡量表(ESS)评分及术后相关并发症发生情况,并比较2组患者的手术成功率。结果:LP组患者治愈1例(5%),显效19例(90%),有效1例(5%),无效0例,手术成功率为95.2%(20/21);SSLPW组患者治愈2例(5.1%),显效33例(84.6%),有效4例(10.3%),无效0例,手术成功率为89.7%(35/39);2组患者手术成功率比较差异无统计学意义(P0.05)。2组患者主观症状均明显改善,术后1个月随访未出现鼻咽部反流及吞咽困难。与术前比较,2组患者术后AHI和ESS评分降低(P0.05),LSaO_2升高(P0.05)。结论:SSLPW联合软腭低温等离子消融术后患者AHI、LSaO_2及ESS评分均改善明显,其可以作为治疗重度OSAHS患者的良好手段。
[Abstract]:Objective: To explore the feasibility and clinical effect of lateral pharyngeal wall suture (SSLPW) combined with soft palate plasma ablation for severe obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: 21 severe OSAHS patients (group LP) and SSLPW combined with lateral wall plasty (LP) combined with soft palate hypothermia plasma ablation were collected. The clinical data of 39 severe OSAHS patients (group SSLPW) treated with soft palate cryogenic plasma ablation were analyzed retrospectively in 2 groups of patients with apnea hypopnea index (AHI), minimum arterial oxygen saturation (LSaO_2), Epworth sleepiness scale (ESS) and postoperative complications, and the operation of 2 groups of patients was compared. Results: in group LP, 1 cases (5%) were cured, 19 cases (90%) were markedly effective, 1 cases were effective (5%), 0 cases were invalid, the operation success rate was 95.2% (20/21); the patients in group SSLPW were cured 2 (5.1%), significant 33 (84.6%), valid 4 cases (19), invalid cases, and the success rate of operation was 35/39 (P0.05) group.2 patients. The subjective symptoms were obviously improved, and no nasopharyngeal reflux and dysphagia were found at 1 months after operation. Compared with the preoperative, the scores of AHI and ESS in the 2 groups were decreased (P0.05) and LSaO_2 increased (P0.05). Conclusion: the AHI, LSaO_2 and ESS scores of patients with SSLPW combined with soft palate hypothermic plasma ablation were improved significantly, which could be used as a treatment for severe OSAHS. The good means of the person.
【作者单位】：锦州医科大学附属火箭军总医院研究生培养基地;中国人民解放军火箭军总医院耳鼻咽喉-头颈外科;
【基金】：中国人民解放军总后勤部卫生局全军“十二五”技术课题面上项目资助课题(CWS11J034);中国人民解放军总后勤部卫生局全军保健专项资助课题(15BJZ23)
【分类号】：R766

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