低温等离子射频与微波两种消融术治疗变应性鼻炎疗效及对鼻腔功能和炎性因子影响的对比分析

发布时间：2018-05-26 07:42

本文选题：微波消融 + 鼻腔功能　；参考：《海南医学院学报》2016年04期

【摘要】：目的:对比低温等离子射频与微波两种消融术治疗重度变应性鼻炎(AR)的疗效及对鼻腔功能和炎性因子影响。方法:选取108例重度AR患者随机分为两组,各54例,分别接受鼻内镜下低温等离子射频(低温射频组)和微波消融(微波消融组)治疗。比较两组治疗前后鼻部症状评分、气道功能指标、鼻腔功能和炎性因子水平。结果:术后3个月低温射频组患者鼻涕、喷嚏、鼻塞、鼻痒、VAS总评分和鼻功能指标MTT和MTR明显低于治疗前和微波消融组,差异具有统计学意义(P0.05);气道功能指标FVC、FEV1、PEF高于治疗前和微波消融组,差异具有统计学意义(P0.05);炎性因子IL-4和IgE低于治疗前和微波消融组,差异具有统计学意义(P0.05);INF-γ高于治疗前和微波消融组,差异具有统计学意义(P0.05)。结论:低温等离子射频消融术可改善重度变应性鼻炎患者临床症状,降低了血清炎症因子水平,提高鼻腔和气道功能,综合疗效优于微波消融治疗。
[Abstract]:Aim: to compare the effect of low temperature plasma radiofrequency ablation and microwave ablation on nasal function and inflammatory factors in patients with severe allergic rhinitis. Methods: one hundred and eight patients with severe AR were randomly divided into two groups, 54 patients in each group were treated with low temperature plasma radiofrequency (RF group) and microwave ablation (microwave ablation group) under nasal endoscope. The scores of nasal symptoms, airway function, nasal function and inflammatory factors before and after treatment were compared between the two groups. Results: the total score of nasal snot, sneeze, nasal obstruction, nasal itching and nasal function index (MTT and MTR) were significantly lower in low temperature radio frequency group than before treatment and microwave ablation group 3 months after operation. The difference was statistically significant (P 0.05), the airway function index (FVC) FEV1 / PEF was higher than that before treatment and microwave ablation group (P 0.05), and the inflammatory factor IL-4 and IgE were lower than those before treatment and microwave ablation group. The difference was statistically significant (P 0.05) compared with that before treatment and microwave ablation group (P 0.05). Conclusion: low temperature plasma radiofrequency ablation can improve the clinical symptoms of patients with severe allergic rhinitis, reduce the level of serum inflammatory factors, improve nasal cavity and airway function, and the comprehensive curative effect is better than microwave ablation.
【作者单位】：湖北省枣阳市第一人民医院耳鼻咽喉科;湖北省枣阳市第一人民医院儿科;
【基金】：湖北省自然基金项目编号(2012-cba036)~~
【分类号】：R765.21

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