非动脉炎性前部缺血性视神经病变诊疗策略及其脉络膜厚度

发布时间：2018-06-02 03:45

本文选题：脉络膜厚度 + 光学相干断层扫描增强深部成像　；参考：《基因组学与应用生物学》2017年09期

【摘要】：非动脉炎性前部缺血性视神经病变(nonarteritic anterior ischemic optic neuropathy,NAION),是一种比较常见视神经疾病,病因、发病机制复杂,治疗效果有限,多年来一直是眼科医生为取得突破性进展而不懈努力的方向。近年来,随着频域相干光断层深度增强成像(enhanced depth imaging spectral-domain optical coherence tomography,EDI-OCT)越来越广泛的应用,为NAION发病机制的研究提供了新的思路:鉴于前部视神经的血供主要来源于睫状后小血管,而这些小血管又构成了脉络膜的主要部分,因此应用EDI-OCT对脉络膜厚度的研究或将为该病发病机制的阐释、治疗效果的评估及预后的随访提供更加便捷的途径。在此,对近年来NAION病因、发病机制、诊断、治疗以及其脉络膜厚度的研究进展进行综述。
[Abstract]:Nonarteritic anterior ischemic optic neuropathy is a common optic nerve disease with complex etiology, complex pathogenesis and limited therapeutic effect. It has been the direction of ophthalmologists for many years to make a breakthrough. In recent years, with the increasing application of enhanced depth imaging spectral-domain optical coherence tomographyEDI-OCTs in frequency domain, it provides a new idea for the study of the pathogenesis of NAION: since the blood supply of the anterior optic nerve mainly comes from the small posterior ciliary vessels, These small vessels constitute the main part of choroid, so the application of EDI-OCT to the study of choroidal thickness may provide a more convenient way to explain the pathogenesis of the disease, evaluate the therapeutic effect and follow up the prognosis. In this paper, the etiology, pathogenesis, diagnosis, treatment and choroidal thickness of NAION are reviewed.
【作者单位】：煤炭总医院;
【基金】：华北理工大学提供资助
【分类号】：R774.6

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