银杏叶片联合高压氧对老年突发性耳聋患者血清CRP水平影响及临床疗效研究

发布时间：2018-06-03 21:42

本文选题：银杏叶片 + 高压氧治疗　；参考：《中华中医药学刊》2017年05期

【摘要】：目的:探讨银杏叶片联合高压氧治疗老年突发性耳聋患者血清CRP水平影响及临床疗效。方法:研究对象为医院耳鼻喉科收治的突发性耳聋老年患者82例,按随机数字表法分组,分别为41例,对照组予以常规治疗,研究组在常规治疗基础上予以银杏叶片联合高压氧治疗,采血测定血清学指标,同时对比临床疗效及并发症。结果:对于治疗前,两组治疗后血清CRP、LPO水平降低,NO、SOD水平升高,T淋巴细胞水平升高,免疫球蛋白水平降低,血液黏度及血小板聚集率降低,HMGB1、ENA-78水平降低,有差异(P0.05);相对于对照组,研究组治疗后血清CRP、LPO水平较低,NO、SOD水平较高,T淋巴细胞水平较高,免疫球蛋白水平较低,血液黏度及血小板聚集率较低,HMGB1、ENA-78水平较低,有差异(P0.05);在临床疗效上,对照组有效率73.17%与研究组有效率90.23%数据对比,有差异(P0.05)。结论:银杏叶片联合高压氧治疗老年突发性耳聋疗效确切,降低血液黏度及血清CRP水平,安全性高。
[Abstract]:Objective: To investigate the effect and clinical effect of Ginkgo Biloba Leaves Extract Tablets combined hyperbaric oxygen (Ginkgo Biloba Leaves Extract Tablets) combined with hyperbaric oxygen (HBO) in the treatment of senile sudden deafness. Methods: 82 cases of sudden deafness in the hospital department of ENT were studied. The study group was divided into 41 cases according to the random number table method, the control group was treated with routine treatment, and the study group was given the routine treatment. With Ginkgo Biloba Leaves Extract Tablets combined hyperbaric oxygen therapy, blood sampling was used to measure serological indexes, and the clinical efficacy and complications were compared. Results: before treatment, serum CRP, LPO level, NO, SOD level, T lymphocyte level, immunoglobulin level decreased, blood viscosity and platelet aggregation rate decreased, HMGB1, ENA-78 level in the two groups before treatment. Compared with the control group, the serum CRP, LPO level was lower, the level of NO, SOD was lower, the level of NO, SOD was higher, the level of T lymphocyte was higher, the level of immunoglobulin was lower, the blood viscosity and platelet aggregation rate were lower, the level of HMGB1, ENA-78 was lower, and there was a difference (P0.05); in the clinical efficacy, the control group was 73.17% and the study group was 73.17%. The efficiency of the 90.23% data was compared with the difference (P0.05). Conclusion: Ginkgo Biloba Leaves Extract Tablets combined hyperbaric oxygen therapy for the treatment of senile sudden deafness is effective, reducing blood viscosity and serum CRP level, high safety.
【作者单位】：新乡医学院第一附属医院耳鼻咽喉头颈外科;
【基金】：河南省重点科技攻关项目(152102310355)
【分类号】：R764.437

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