睑板腺功能障碍患者的视觉质量分析

发布时间：2018-06-04 05:17

本文选题：睑板腺功能障碍 + 干眼　；参考：《眼科新进展》2017年10期

【摘要】：目的运用双通道视觉质量分析仪(optical quality analysis system,OQAS-Ⅱ)观察睑板腺功能障碍(meibomian gland dysfunction,MGD)患者的视觉质量,为其临床应用提供依据。方法 50例(50眼)MGD患者按照是否伴随干眼症状分为MGD干眼组(22眼)和MGD非干眼组(28眼),同时选取25名(25眼)健康志愿者为对照组。利用OQAS-Ⅱ检测并比较3组受试者自然状态下的视觉质量:调制传递函数截止频率(modulation transfer function cutoff,MTF cutoff)、斯特列尔比值(Strehl ratio,SR)、客观散射指数(objective scattering index,OSI)。所有受试对象均行睑板腺相关检查(睑缘形态评分、睑板腺挤压评分、睑板腺分泌物性状评分)和泪液相关检查。对3组受试对象的测量结果进行比较,同时检测指标间的相关性。结果 3组受试对象的MTF cutoff、SR、OSI差异均有统计学意义(均为P0.05)。MGD非干眼组的MTF cutoff和SR分别为(31.36±1.83)c·deg~(-1)和0.21±0.02,均较对照组的(35.87±1.59)c·deg~(-1)和0.23±0.03显著降低,OSI为0.57±0.06,较对照组的0.45±0.06显著提高(均为P0.05);MGD干眼组的MTF cutoff和SR分别为(27.87±3.08)c·deg~(-1)和0.16±0.02,均较MGD非干眼组显著降低,OSI为0.72±0.10,较MGD非干眼组显著提高(均为P0.05)。MGD患者的OSI、MTF cutoff、SR与泪膜破裂时间、泪液分泌量、睑板腺相关检查数据间均无相关性(均为P0.05)。结论 OQAS-Ⅱ检测发现MGD患者的视觉质量参数发生变化,且MGD干眼患者较MGD非干眼患者变化更明显。MGD非干眼患者视觉质量的下降应当引起临床医师的重视。
[Abstract]:Objective To observe the visual quality of the tarsal gland dysfunction (meibomian gland dysfunction, MGD) patients with optical quality analysis system (OQAS- II), and to provide a basis for its clinical application. Methods 50 cases (50 eyes) were divided into MGD dry eye (22 eyes) and MGD non dry eyes (22 eyes) in accordance with the symptoms of dry eye (50 eyes). At the same time, 25 (25 eyes) healthy volunteers were selected as the control group. OQAS- II was used to detect and compare the visual quality of the subjects in the natural state of the 3 groups: the cut-off frequency of the modulation transfer function (modulation transfer function cutoff, MTF cutoff), the SRL ratio (Strehl ratio, SR), and the objective scattering index (objective scattering). All subjects underwent palpebral gland correlation examination (palpebral morphology score, palpebral gland extrusion score, palpebral gland secretion character score) and tear correlation examination. The results of the 3 groups were compared, and the correlation between the indexes was detected. Results the differences in MTF cutoff, SR, and OSI were statistically significant (P 0.05) the MTF cutoff and SR in the.MGD non dry eye group were (31.36 + 1.83) C. Deg~ (-1) and 0.21 + 0.02 respectively, which were significantly lower than those of the control group (35.87 + 1.59) C. Deg~ (-1) and 0.23 + 0.03. The OSI was 0.57 + 0.06, compared with 0.45 + 0.06 in the control group (P0.05), respectively. Compared with MGD non dry eye group, OSI was 0.72 + 0.10, compared with MGD non dry eye group (all P0.05), OSI, MTF cutoff, SR and tear film rupture time, tear secretion, and eyelid gland related examination data were not related (all P0.05). Conclusion OQAS- II detection found that the visual quality parameters of the MGD patients were changed. Dry eye patients are more sensitive than non dry eye patients in MGD. The decrease of visual quality in.MGD non dry eye patients should attract clinicians' attention.
【作者单位】：南京总医院眼科;
【分类号】：R777.13

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