经皮颏舌肌电刺激治疗对悬雍垂腭咽成形术后的轻中度阻塞性睡眠呼吸暂停综合征的疗效观察

发布时间：2018-06-10 15:16

本文选题：经皮电刺激 + 颏舌肌　；参考：《南京医科大学》2015年硕士论文

【摘要】：目的:评价无创经皮颏舌肌电刺激对悬雍垂腭咽成形术后(Uvulopalatopharyngoplasty,UPPP)仍残留轻中度阻塞性睡眠呼吸暂停综合征(Obstructive sleep apnea syndrome,OSAS)患者的疗效。方法:选择23例UPPP术后经多导睡眠监测(PSG)显示仍存留轻中度OSAS的患者,夜间给予经皮颏舌肌电刺激治疗。分别在治疗前及治疗时行多导睡眠监测(Polysomnography,PSG),并依据Epworth睡眠量表(Epworth sleepiness scale,ESS)给OSAS患者进行嗜睡评分;然后比较治疗前及治疗中的PSG参数及治疗对白日嗜睡评分有无统计学差异。结果:与治疗前相比,OSAS患者治疗中的夜间呼吸暂停低通气指数(Apnea hypopnea index,AHI)、微觉醒指数(Microarousal index,MAI)、睡眠期间SpO2低于90%时间占总睡眠时间的百分比(T90)及白日的ESS评分降低(9.2±4.2比17.9±6.9,P=0.000;6.3±3.8比10.9±4.9,P=0.000;4.9%±4.0%比9.1%±4.2%,P=0.000;8.7±3.4比9.3±3.1,P=0.002),并且平均SpO2和最低SpO2均显著升高(95.5%±1.0%比94.4%±1.1%,P=0.000;88.7%±2.9%比85.2%±4.7%,P=0.000);患者治疗中无明显不适主诉。结论:经皮颏舌肌电刺激治疗可以改善OSAS患者睡眠呼吸紊乱及白日嗜睡状况,其对UPPP术后仍存留轻中度OSAS的患者不失为一种安全、有效的治疗方法。
[Abstract]:Objective: to evaluate the efficacy of noninvasive genioglossus electromyography in patients with mild to moderate obstructive sleep apnea syndrome (OSAs) after uvulopalatopharyngoplasty. Methods: Twenty-three patients with mild to moderate OSAS were treated with percutaneous genioglossus electromyography (PSG) after UPPP. Polysomnography PSG was performed before and after treatment, and the somnolence scores were evaluated according to Epworth sleepiness scale, and then the parameters of PSG before and during treatment were compared. Results: compared with before treatment, the nocturnal apnea hypopnea index (Apnea hypopnea index), microarousal index (microarousal index), the percentage of SPO 2 less than 90% of total sleep time (T90) and the daytime ESS score decreased by 9.2 卤4.2 vs 17.9 卤6.9P0. 000g / L and 6.3 卤3.8 respectively. Compared with 10.9 卤4.9% 卤4.0% 卤4.1% 卤4.2%, 8.7 卤3.4 vs 9.3 卤3.1 P0. 002, the average SPO 2 and the lowest SPO 2 were significantly increased by 95.5% 卤1.0% vs 94.4% 卤1.1 P0.0007% 卤2.9% vs 85.2% 卤4.7% respectively. Conclusion: percutaneous genioglossal electromyography stimulation can improve sleep apnea disorder and daytime sleepiness in patients with OSAS. It is a safe and effective treatment for patients with mild to moderate OSAS after UPPP.
【学位授予单位】：南京医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R766.9

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