睡眠呼吸障碍儿童气道炎症的初步研究

发布时间：2018-06-13 11:57

本文选题：鼻呼出气一氧化氮 + 睡眠呼吸紊乱　；参考：《临床耳鼻咽喉头颈外科杂志》2017年09期

【摘要】：目的:探讨鼻呼出气一氧化氮值(NNO)对睡眠呼吸障碍(SDB)儿童诊断的临床意义,评估SDB儿童气道炎症的严重程度。方法:选取SDB患儿30例、健康儿童20例为研究对象,用瑞典NIOX MINO仪器无创检测受试者的NNO值。以SPSS 20.0统计软件进行数据分析。结果:与健康儿童相比,SDB患儿的NNO值升高,差异有统计学意义(Z=-2.215,P0.05)。在SDB患儿中,NNO值与其AHI值呈正相关(r=0.429,P0.05),与夜间最低血氧值呈负相关(r=-0.482,P0.01),与其他睡眠参数无相关性。结论:NNO值是反映SDB患儿气道炎症严重程度的潜在指标。
[Abstract]:Objective: to investigate the clinical significance of nasal exhalation nitric oxide (no) in children with sleep apnea disorder (SDBs) and to evaluate the severity of airway inflammation in children with SDB. Methods: 30 cases of SDB and 20 cases of healthy children were selected. The data were analyzed by SPSS 20.0 software. Results: compared with healthy children, the value of NNO in children with SDB was significantly higher than that in children with SDB, and the difference was statistically significant (P 0.05). There was a positive correlation between NNO and AHI in SDB, a negative correlation between NNO and nocturnal minimum blood oxygen, and no correlation with other sleep parameters. Conclusion the ratio of N to N is a potential indicator to reflect the severity of airway inflammation in children with SDB.
【作者单位】：广东省妇幼保健院耳鼻咽喉科;
【基金】：广东省医学科学技术研究基金项目(No:A2015343)
【分类号】：R766

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