不同海拔地区藏、汉族OSAS患者冠状动脉及颈动脉的病变程度比较

发布时间：2018-06-13 13:41

本文选题：阻塞性睡眠呼吸暂停综合征 + 冠状动脉　；参考：《山东医药》2017年33期

【摘要】：目的探讨不同海拔地区藏、汉族阻塞性睡眠呼吸暂停综合征(OSAS)患者冠状动脉及颈动脉病变程度的差异。方法选取西宁地区(平均海拔2 260m)和玉树地区(平均海拔3 000 m)OSAS患者78例,依据海拔、民族不同分为西宁汉族组21例、西宁藏族组19例、玉树汉族组18例、玉树藏族组20例。对四组行24 h动态血压监测,检测平均收缩压、平均舒张压、24 h收缩压变异系数、日间收缩压变异系数、夜间收缩压变异系数、24 h舒张压变异系数、日间舒张压变异系数、夜间舒张压变异系数;行冠状动脉CT检查,采用Gensini加权积分评价冠状动脉狭窄程度;行颈动脉血管彩超检查,采用Crouse加权积分评价颈动脉病变程度。结果玉树藏、汉族组24 h舒张压变异系数分别高于西宁同民族组,差异有统计学意义(P均0.05);西宁藏、汉族组冠状动脉狭窄程度Gensini积分及颈动脉病变Crouse积分高于玉树同民族组,差异有统计学意义(P均0.05);同海拔地区不同民族组冠状动脉狭窄程度Gensini积分及颈动脉病变Crouse积分无差异(P均0.05)。结论不同海拔地区藏、汉族OSAS患者冠状动脉及颈动脉病变程度存在差异,同海拔环境下藏、汉族OSAS患者冠状动脉及颈动脉病变程度无差别。
[Abstract]:Objective to investigate the degree of coronary artery and carotid artery lesions in patients with obstructive sleep apnea syndrome (OSAS) in different altitude. Methods Seventy-eight patients with OSAS in Xining area (mean altitude 2260 m) and Yushu area (mean altitude 3 000 m) were divided into Xining Han nationality group (21 cases), Xining Tibetan group (19 cases), Yushu Han nationality group (18 cases) and Yushu Tibetan group (20 cases). 24 h ambulatory blood pressure monitoring was performed in the four groups. The mean systolic blood pressure, the mean diastolic blood pressure at 24 h, the daytime systolic blood pressure variation coefficient, the night systolic blood pressure variation coefficient at 24 h, the daytime diastolic blood pressure variation coefficient at 24 h, and the daytime diastolic blood pressure variation coefficient were measured. The variation coefficient of nighttime diastolic blood pressure was evaluated by coronary CT, and the degree of coronary artery stenosis was evaluated by Gensini weighted score, carotid artery color Doppler ultrasonography and Crouse weighted score. Results the coefficient of variation of diastolic blood pressure in Yushu Tibet group and Han nationality group was higher than that in Xining nationality group (P < 0.05), the Gensini score of coronary artery stenosis and the carotid artery lesion Crouse score in Xining Tibetan and Han nationality group were higher than those in Yushu nationality group. There was no significant difference in Gensini score and Crouse score of coronary artery stenosis in different ethnic groups at the same altitude, and there was no significant difference in Gensini score and Crouse score for carotid artery lesions in different ethnic groups at the same altitude. Conclusion the degree of coronary artery and carotid artery lesions in patients with OSAS in Han nationality is different from that in different altitude areas, but there is no difference in the degree of coronary artery and carotid artery lesions in patients with OSAS in Han nationality at the same altitude.
【作者单位】：保定市第二中心医院;青海省人民医院;
【基金】：青海省科学技术厅(应用)基础研究计划项目(2014-ZJ-741)
【分类号】：R766

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