儿童阻塞性睡眠呼吸暂停低通气综合征与肥胖的相关性研究

发布时间：2018-06-23 10:42

本文选题：阻塞性呼吸睡眠暂停/低通气综合征 + 肥胖　；参考：《现代生物医学进展》2016年24期

【摘要】：目的:探讨儿童阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)与肥胖的相关性。方法:收集单纯性肥胖儿童120例和体重正常儿童110例作为研究对象,进行统一的体格检查和专科检查,并进行多导睡眠监测记录阻塞性呼吸暂停指数(OAI)、呼吸暂停/低通气指数(AHI)、中枢性呼吸暂停指数(CAI)、最低血氧饱和度(LSa O2)和睡眠效率。结果:肥胖组OSAHS患病率为58.33%显著高于对照组的31.82%,差异有统计学意义(P0.05);OAI、AHI、CAI均显著高于对照组,而LSa O2、睡眠效率指标显著低于对照组,差异均有统计学意义(均P0.05);多因素回归分析显示,肥胖、扁桃体增生、腺样体增生是导致OSAHS的独立危险因素,差异有统计学意义(均P0.05)。结论:肥胖是儿童OSAHS发病的重要影响因素,特别是合并扁桃体肿大或腺样体肿大的患儿应注意预防OSAHS的发生。
[Abstract]:Objective: to investigate the relationship between obstructive sleep apnea / hypopnea syndrome (OSAHS) and obesity. Methods: 120 children with simple obesity and 110 children with normal body weight were collected as study subjects. The obstructive apnea index (OAI), apnea / hypopnea index (AHI), central apnea index (CAI), minimum oxygen saturation (LSAO _ 2) and sleep efficiency were recorded by polysomnography. Results: the prevalence rate of OSAHS in obesity group was 58.33%, significantly higher than that in control group (31.822%). The difference was statistically significant (P0.05). Multivariate regression analysis showed that obesity, tonsil hyperplasia and adenoid hyperplasia were independent risk factors for OSAHS (P0.05). Conclusion: obesity is an important factor in the pathogenesis of OSAHS in children, especially in children with tonsillar enlargement or adenoidomegaly should be paid attention to prevent the occurrence of OSAHS.
【作者单位】：新疆医科大学第一附属医院儿科;乌鲁木齐儿童医院风湿免疫科;乌鲁木齐儿童医院耳鼻喉科;
【分类号】：R766;R723.14

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