阻塞性睡眠呼吸暂停低通气综合征患者上气道MRI测量值与其病情严重程度的相关性研究

发布时间：2018-06-25 16:42

本文选题：睡眠呼吸暂停 + 阻塞性　；参考：《中国耳鼻咽喉头颈外科》2016年04期

【摘要】：目的研究阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者清醒状态下的上气道MRI测量值与其病情严重程度评价指标的相关性,并评估其临床意义。方法对37例OSAHS患者及18例正常人进行清醒状态下上气道的MRI扫描,并对咽腔相关参数进行测量,比较OSAHS患者及正常人上气道结构的差异。并将咽腔测量参数与OSAHS严重程度评价指标(呼吸暂停低通气指数、最低血氧饱和度、氧减饱和度指数)进行相关性研究。结果 OSAHS患者软腭后区气道截面积及左右径、咽侧壁长度、舌体长度、舌根宽度、软腭长度、软腭厚度及软腭在正中矢状位的截面的面积与呼吸暂停低通气指数、最低血氧饱和度及氧减饱和度指数具有相关性(P均0.05)。结论上气道MRI扫描所获得的形态学测量数据可在一定程度上评估OSAHS的严重程度,对判定阻塞平面及选择治疗方案具有重要的指导意义。
[Abstract]:Objective to study the correlation between MRI measurements of upper airway in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and the severity of OSAHS and evaluate its clinical significance. Methods 37 patients with OSAHS and 18 normal subjects were examined with MRI and the parameters of pharyngeal cavity were measured to compare the structure of upper airway between OSAHS patients and normal subjects. The correlation between the parameters of pharyngeal cavity measurement and the severity of OSAHS (apnea hypopnea index, minimum oxygen saturation, oxygen desaturation index) was studied. Results the airway cross-sectional area, left and right diameter of posterior soft palate, length of lateral pharyngeal wall, length of tongue body, width of tongue root, length of soft palate, thickness of soft palate, area of soft palate section in median sagittal position and apnea hypopnea index were found in OSAHS patients. The lowest oxygen saturation and oxygen desaturation index were correlated (P 0.05). Conclusion the morphologic data obtained from MRI scan of upper airway can evaluate the severity of OSAHS to some extent and have important guiding significance in judging the obstruction plane and choosing the treatment plan.
【作者单位】：东南大学附属中大医院耳鼻咽喉头颈外科;南京医科大学附属南京儿童医院放射科;东南大学附属中大医院放射科;
【分类号】：R766;R445.2

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