糖尿病性黄斑水肿视网膜功能定量研究

发布时间：2018-06-26 23:09

本文选题：糖尿病性黄斑水肿 + 多焦视网膜电图　；参考：《国际眼科杂志》2016年09期

【摘要】：目的:应用多焦视网膜电图评估糖尿病性黄斑水肿的视网膜功能。方法:选取2010-03/2014-03我院眼科经眼底血管造影检查确诊为糖尿病性黄斑水肿的患者30例48眼为观察组(其中局限性水肿18眼,弥漫性水肿24眼,囊样水肿6眼),选取视力0.8以上,经裂隙灯显微镜检查均未发现异常,全身情况无异常者15例30眼为对照组,两组研究对象均行多焦视网膜电图检查,并对其结果进行统计学分析。结果:糖尿病性黄斑水肿组多焦视网膜电图中心凹、黄斑区、黄斑外区a、b波的振幅密度与对照组相比均差异存在统计学意义(P0.01);中心凹处观察组和对照组a波的振幅密度分别为25.2±10.48、37.93±7.19nv/deg2,b波的振幅密度分别为77.16±27.97、113.42±11.79nv/deg2;黄斑区观察组和对照组a波的振幅密度分别为14.27±4.99、27.42±2.86nv/deg2,b波的振幅密度分别为43.14±14.77、69.99±10.07 nv/deg2;黄斑外区观察组和对照组a波的振幅密度分别为7.82±2.79、11.46±1.54nv/deg2,b波的振幅密度分别为19.85±6.5、31.56±6.0nv/deg2。中心凹处、黄斑区及黄斑外区多焦视网膜电图a、b波振幅密度在局限性黄斑水肿组与弥漫性黄斑水肿组和囊样黄斑水肿组间均存在统计学意义(P0.01)。结论:糖尿病性黄斑水肿的多焦视网膜表现为a、b波振幅密度下降,潜伏期延长,振幅密度比潜伏期敏感。
[Abstract]:Objective: to evaluate the retinal function of diabetic macular edema by multi-focal electroretinogram. Methods: thirty patients (48 eyes) with diabetic macular edema (18 eyes of local edema, 24 eyes of diffuse edema, 6 eyes of cystic edema) were selected as the observation group. The visual acuity was more than 0.8 in 30 patients with diabetic macular edema confirmed by fundus angiography in 2010-03 / 2014-03 ophthalmology, including 18 eyes of localized edema, 24 eyes of diffuse edema and 6 eyes of cystic edema. No abnormality was found by slit lamp microscope, and 15 cases (30 eyes) with no abnormal systemic condition were taken as the control group. The two groups were examined by multifocal electroretinogram, and the results were analyzed statistically. Results: in diabetic macular edema group, the central fovea, macular area, and multifocal electroretinogram were observed. The amplitude density of a b wave in the extramacular area was significantly different from that in the control group (P0.01), the amplitude density of a wave in the fovea observation group and the control group was 25.2 卤10.4837.93 卤7.19nv / deg2b wave, respectively, 77.16 卤27.97113.42 卤11.79nv / deg2nvdeg2 in the macular area observation group and control group, and in the macular area observation group and the control group, the amplitude density was 77.16 卤27.97113.42 卤11.79nv / deg2, respectively. The amplitude densities of a wave were 14.27 卤4.99 卤27.42 卤2.86 nvdeg2b and 7.82 卤2.79 11.46 卤1.54 nvdeg2b, 19.85 卤6.5nvdeg2b and 19.85 卤6.5 卤6.56 卤6.0nvr / deg2, respectively, and the amplitude densities of a wave were 7.82 卤2.7911.46 卤1.54nvdeg2b, respectively, and the amplitude densities of a wave were 19.85 卤6.5nv-31.56 卤6.0nvrdeg2nvdeg2.The amplitude densities of a wave were 7.82 卤2.7911.46 卤1.54nvdeg2b and 19.85 卤6.5nv-31.56 卤6.0nvrdeg2 respectively. There was a significant difference in the amplitude density of afib wave between localized macular edema group, diffuse macular edema group and cystic macular edema group (P0.01). Conclusion: the multifocal retinal manifestations of diabetic macular edema are the decrease of amplitude density, the prolongation of latency and the sensitivity of amplitude density to latency.
【作者单位】：中国河北省石家庄市第一医院眼科;
【分类号】：R587.2;R774

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