手法小切口白内障手术对糖尿病白内障患者角膜变化的影响

发布时间：2018-06-29 20:54

本文选题：糖尿病 + 白内障　；参考：《中国现代医学杂志》2017年13期

【摘要】：目的手法小切口白内障手术(MSICS)对糖尿病白内障患者角膜内皮细胞和角膜厚度变化的影响。方法 60例2型糖尿病白内障患者60只眼睛(糖尿病组)以及60例年龄匹配的非糖尿病棕色白内障60只眼睛(对照组)接受MSICS。术前、术后1、6和12周采用非接触角膜内皮显微镜检测所有患者角膜内皮细胞及角膜中央厚度。并且评估角膜内皮细胞形态学和六角形细胞百分比变化。结果对照组术前平均角膜内皮细胞计数高于糖尿病组(P0.05)。两组术后角膜内皮细胞均减少(单因素方差分析P0.05)。糖尿病组术后角膜内皮细胞数的减少(14.19%,P0.05)高于非糖尿病组(8.05%)。糖尿病组角膜中央厚度增加大于对照组(P0.05)。糖尿病组六角形细胞百分比的变化大于对照组(P0.05)。组间变异系数的差异无统计学意义(P0.05)。结论与非糖尿病患者相比,糖尿病患者MSICS术后角膜内皮细胞损伤更多。建议糖尿病患者接受眼内手术前,对角膜内皮细胞进行评估。
[Abstract]:Objective to study the effect of manual small incision cataract surgery (MSICS) on corneal endothelium and corneal thickness in diabetic cataract patients. Methods 60 eyes of 60 patients with type 2 diabetic cataract (diabetic group) and 60 eyes of age-matched non-diabetic brown cataract (control group) were treated with MSICS. The corneal endothelial cells and central corneal thickness were measured by non-contact keratoendothelium microscope before and 1 and 12 weeks postoperatively. The changes of corneal endothelial cell morphology and percentage of hexagonal cells were evaluated. Results the average corneal endothelial cell count in the control group was higher than that in the diabetic group (P 0.05). Corneal endothelial cells were decreased in both groups (single factor analysis of variance P 0.05). The number of corneal endothelial cells in diabetic group (14.19%) was significantly higher than that in non-diabetic group (8.05%). The central corneal thickness in the diabetic group was higher than that in the control group (P0.05). The change of the percentage of hexagonal cells in the diabetic group was greater than that in the control group (P0.05). There was no significant difference in coefficient of variation between groups (P0.05). Conclusion compared with the non-diabetic patients, the corneal endothelial cells in the diabetic patients after MSICS are more damaged. It is recommended that corneal endothelial cells be evaluated before intraocular surgery in diabetic patients.
【作者单位】：南华大学附属第二医院眼科;南华大学附属第二医院血液肿瘤科;
【分类号】：R779.66

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