视网膜静脉阻塞的危险因素分析

发布时间：2018-07-02 20:23

本文选题：视网膜中央静脉阻塞 + 视网膜分支静脉阻塞　；参考：《眼科新进展》2017年06期

【摘要】：目的分析视网膜中央静脉阻塞(central retinal vein occlusion,CRVO)和视网膜分支静脉阻塞(branch retinal vein occlusion,BRVO)的危险因素;并对CRVO和BRVO危险因素进行直接比较。方法对46例CRVO(CRVO组)、33例BRVO(BRVO组)与79例老年性白内障或屈光不正患者(对照组)行危险因素和血脂谱分析,并对比观察。结果多元线性回归分析结果显示:高同型半胱氨酸血症(P0.000 1)、高总胆固醇(P=0.003 0)、高脂蛋白a(P=0.027 0)、高血压(P=0.022 0)、短眼轴(P0.000 1)与CRVO显著相关;而高同型半胱氨酸血症(P0.000 1)、高总胆固醇(P=0.008 0)、高血压(P=0.002 0)、高体质量指数(P=0.004 0)、短眼轴(P=0.001 0)与BRVO相关。一元线性回归分析示CRVO和BRVO上述危险因素比较没有明显差别。结论 CRVO、BRVO危险因素包括系统(高血脂、高血压、高同型半胱氨酸)和眼部(短眼轴)的多种因素,但是这些危险因素在CRVO和BRVO之间没有显著差异。
[Abstract]:Objective to analyze the risk factors of central retinal vein occlusion (central retinal vein occlusion) and retinal branch vein occlusion (branch retinal vein occlusion BRVO), and to compare the risk factors of CRVO and BRVO directly. Methods the risk factors and blood lipid profile of 46 patients with CRVO (CRVO group), 33 patients with BRVO (BRVO group) and 79 patients with senile cataract or ametropia (control group) were analyzed and compared. Results multiple linear regression analysis showed that hyperhomocysteinemia (P0.000 1), high total cholesterol (P0. 0030), high lipoprotein a (P0. 0270), hypertension (P0. 0220), short eye axis (P0. 000 1) were significantly associated with CRVO. Hyperhomocysteinemia (P0. 000 1), high total cholesterol (P0. 0080), hypertension (P0. 0020), high body mass index (P0. 0040) and short eye axis (P0. 001 0) were associated with BRVO. Univariate linear regression analysis showed no significant difference between CRVO and BRVO risk factors. Conclusion CRVO BRVO risk factors include systemic (hyperlipidemia, hypertension, high homocysteine) and eye (short eye axis), but there is no significant difference between CRVO and BRVO.
【作者单位】：昆明医科大学第一附属医院眼科;汕尾亮睛工程眼科医院眼科;南昌大学第二附属医院眼科;
【基金】：国家自然科学基金(编号:81260151) 云南省应用基础研究计划项目(编号:2016FB126) 云南省科技厅科技惠民计划项目(编号:2014RA009)~~
【分类号】：R776.1;R778.1

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