Tolosa-Hunt综合征10例临床诊治分析

发布时间：2018-07-11 15:22

本文选题：Tolosa-Hunt综合征 + 海绵窦　；参考：《临床和实验医学杂志》2016年10期

【摘要】：目的研究Tolosa-Hunt综合征(THS)的病因、诊断及治疗。方法收集2010年至2014年住院诊断10例Tolosa-Hunt综合征患者的临床表现、神经影像学、实验室检查及激素治疗情况并进行回顾性分析。结果 10例患者的颅神经麻痹累及动眼神经、滑车神经、外展神经及三叉神经第1、2、3支,有1例为完全性动眼神经麻痹。10例患者神经影像学分类均为良性的,应用激素后疼痛快速减轻,仅有1例遗留轻度复视。对治疗反应无年龄及性别差异。应用激素后10例患者疼痛均较眼肌麻痹缓解快。结论 THS的诊断为排他性,神经影像学对于鉴别诊断THS非常重要,对于THS病人应全面完善检查除外其他疾病引起的疼痛性眼肌麻痹,包括血常规、红细胞沉降率、C反应蛋白、甲状腺、肝肾功能检查、胸片、头部及眼眶部CT及磁共振检查。
[Abstract]:Objective to study the etiology, diagnosis and treatment of Tolosa-Hunt syndrome (THS). Methods from 2010 to 2014, 10 patients with Tolosa-Hunt syndrome were collected and analyzed retrospectively, including clinical manifestation, neuroimaging, laboratory examination and hormone therapy. Results the cranial nerve palsy involved the oculomotor nerve, the trochlear nerve, the abducens nerve and the trigeminal nerve. The pain was relieved quickly after hormone application, and only 1 case had mild diplopia. There was no age or gender difference in response to treatment. The pain relief of 10 patients was faster than that of ophthalmoplegia. Conclusion the diagnosis of THS is exclusive, neuroimaging is very important for differential diagnosis of THS, and should be comprehensive and perfect for THS patients except pain ophthalmoplegia caused by other diseases, including blood routine examination, erythrocyte sedimentation rate and C-reactive protein. Thyroid, liver and kidney function examination, chest film, head and orbit CT and magnetic resonance imaging.
【作者单位】：首都医科大学附属北京友谊医院神经内科;
【分类号】：R777.45

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