294例炎症性肠病临床特点及随访分析

发布时间：2018-01-05 09:30

本文关键词：294例炎症性肠病临床特点及随访分析　出处：《第三军医大学学报》2016年08期 　论文类型：期刊论文

【摘要】：目的总结我院10年间炎症性肠病(inflammatory bowel disease,IBD)住院患者的流行病学特点、临床表现以及疾病预后情况。方法收集我院10年间294例住院IBD患者的临床资料,并电话随访其上皮内瘤变、手术及死亡率,分析溃疡性结肠炎(ulcerative colitis,UC)及克罗恩病(Crohn’s disease,CD)患者流行病学、临床表现及疾病预后的特点。结果 10年间我院IBD患者住院人数有逐年上升的趋势,两者均好发于青壮年人群,发病无明显性别倾向性(P0.05);临床及肠镜表现上,UC以腹泻、血便、里急后重、黏膜充血水肿、糜烂表现为主,CD则主要表现为腹部包块、息肉样病变、肠管僵硬/狭窄及铺路石样结节,差异具有统计学意义(P0.05);UC手术肠管切除率明显低于CD,差异具有统计学意义(P0.05),但两者在低级别上皮内瘤变率及死亡率上相似,差异无统计学意义(P0.05)。结论 UC及CD均好发于青壮年人群,发病无明显性别倾向性;临床上UC主要以肠道粘膜受损为突出表现,而CD则以肠道增殖性病损表现为主;两者在低级别上皮内瘤变率及死亡率上相似,但UC手术肠管切除率明显低于CD。
[Abstract]:Objective to summarize the epidemiological characteristics of inflammatory bowel disease (bowel) inpatients in our hospital during the past 10 years. Methods the clinical data of 294 inpatients with IBD in our hospital during the past 10 years were collected, and their intraepithelial neoplasia, surgery and mortality were followed up by telephone. To analyze the epidemiology of ulcerative colitis (UCC) and Crohns disease (CDCD) in patients with ulcerative colitis. Results the number of inpatients with IBD in our hospital increased year by year during the past 10 years, both of them were more common in the young and middle-aged population, and there was no obvious sexual tendency in the onset of the disease (P0.05). The clinical and endoscopic manifestations of UC were diarrhea, blood stool, acute and severe, hyperemia and edema of mucous membrane, erosion mainly presented as abdominal mass and polypoid lesion. There were significant differences in the stiffness / stenosis of the intestine and the paving stone nodules (P 0.05). The rate of intestinal resection in UC was significantly lower than that in CD.There was a statistically significant difference (P 0.05), but the rates of intraepithelial neoplasia and mortality were similar between the two groups. Conclusion UC and CD are more common in the young and adult population, and there is no obvious sexual tendency in the onset of the disease. In clinic UC was mainly characterized by intestinal mucosal damage while CD was mainly characterized by intestinal proliferative and venereal diseases. The rate of low grade intraepithelial neoplasia and mortality were similar, but the rate of intestinal resection in UC was significantly lower than that of CD.
【作者单位】：第三军医大学大坪医院野战外科研究所消化内科;
【基金】：国家自然科学基金青年基金(81500408) 第三军医大学大坪医院野战外科研究所临床科研基金(2014YLC05)~~
【分类号】：R574.62
【正文快照】： 第三军医大学大坪医院野战外科研究所消化内科)Research,Daping Hospital of Third Military Medical University(2014YLC05).Corresponding author:Chen Dongfeng,E-mail:chendf1981@126.com炎症性肠病(inflammatory bowel disease,IBD)是一类病因不明且主要累及肠道的特发性

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