自拟健脾养胃方辅助治疗慢性萎缩性胃炎效果观察

发布时间：2018-01-26 22:06

本文关键词： 慢性萎缩性胃炎中药疗法健脾养胃幽门螺杆菌　出处：《山东医药》2016年34期 　论文类型：期刊论文

【摘要】：目的观察自拟健脾养胃方辅助治疗慢性萎缩性胃炎(CAG)的临床效果。方法将84例CAG患者随机分为观察组和对照组各42例,均采用奥美拉唑、替硝唑、克拉霉素及枸橼酸铋钾联合治疗,1周后停服,口服瑞巴派特至第8周;观察组同时口服自拟健脾养胃中药汤剂8周。治疗前后,观察两组临床疗效及胃镜下各种征象积分。治疗第4周后,两组行14C尿素呼气试验观察幽门螺杆菌(Hp)根除情况。结果观察组临床疗效总有效率95.24%、Hp根除率80.95%,对照组分别为76.19%、50.00%,P均0.05。治疗后两组胃镜下各种征象积分均较治疗前降低,观察组较对照组降低更明显,P均0.05。结论在常规治疗CAG基础上应用自拟健脾养胃方,能提高临床疗效和Hp根除率,改善胃镜下表现。
[Abstract]:Objective to observe the clinical effect of self-made Jianpi Yangwei recipe in the treatment of chronic atrophic gastritis. Methods Eighty-four patients with CAG were randomly divided into observation group (n = 42) and control group (n = 42), all of whom were treated with omeprazole. Tinidazole, clarithromycin and bismuth potassium citrate were given orally for 8 weeks. Observe the clinical effect of the two groups before and after treatment and observe the integration of various signs under gastroscopy. After 4 weeks of treatment, the observation group took orally the traditional Chinese medicine decoction of invigorating spleen and nourishing stomach for 8 weeks. The eradication of Helicobacter pylori (HP) was observed by 14C urea breath test. Results the total effective rate of the observation group was 95.24% and the eradication rate of HP was 80.95%. After treatment, the scores of various signs under gastroscopy in the two groups were lower than those before treatment, and the decrease in the observation group was more obvious than that in the control group. Conclusion on the basis of routine treatment of CAG, the self-made prescription of invigorating spleen and nourishing stomach can improve the clinical efficacy and HP eradication rate, and improve the performance of gastroscope.
【作者单位】：青岛市第八人民医院;
【分类号】：R573.32
【正文快照】： 随着现代药理学的进展,祖国传统医学中多味中药材对胃黏膜的保护、修复作用被认知,并被用于临床实践[1,2]。受此启发笔者自拟健脾养胃方,并从我院2012年2月~2015年10月收治的慢性萎缩性胃炎(CAG)患者中抽取84例进行分组对照研究,以观察自拟健脾养胃方联合西药治疗CAG的临床效

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