缺血性结肠炎与溃疡性结肠炎对比分析

发布时间：2018-02-25 07:29

本文关键词： 缺血性结肠炎溃疡性结肠炎对比分析　出处：《广西医科大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的：对比分析缺血性结肠炎(IC)与溃疡性结肠炎(UC)的临床、实验室、内镜、组织病理学及影像学等检查的差异,寻找两者的鉴别点,以利于缺血性结肠炎与溃疡性结肠炎临床治疗。方法：收集2010年1月～2013年12月在广西医科大学第一附属医院就诊的20例缺血性结肠炎患者及30例溃疡性结肠炎患者,统计两组患者的性别、年龄、病程、基础疾病史、临床表现,肠镜结果、组织病理特点及影像学等资料,分析它们对两种疾病是否有鉴别意义。结果：缺血性结肠炎与溃疡性结肠炎两组间的年龄、病程和基础疾病比较差异有统计学意义(P0.05),其中IC组以老年人多见,病程短,多伴发心脑血管等基础疾病(14/20,70%),UC组以中青年多见,病程长,多不伴有心脑血管等基础疾病。在临床表现方面,IC组鲜血便多见,而UC组黏液血便、里急后重多见,两者差异具有统计学意义(P0.05)。在化验方面,IC组C反应蛋白水平(30.54±11.12)ng/ml高于UC组(7.65±2.54)ng/ml,而IC组血小板水平(170.5±50.2)×109/L低于UC组(310.8±86.4)×109/L,差异具有统计学意义(P0.05)。内镜下IC组病变呈纵行、分界清、非连续性的比例高于UC组,两者比较差异具有统计学意义(P0.05),病理呈现为腺瘤样息肉、隐窝炎和脓肿的比例低于UC组,两者比较差异具有统计学意义(P0.05)。结论：临床上IC病程长、解鲜血便,UC病程短、粘液血便为主,内镜下IC病变局限呈纵行、分界清、非连续性,UC病变广泛,易累及直肠,溃疡呈地图状,病理方面UC较IC可有腺瘤样增生、隐窝炎和脓肿,为两者的主要鉴别点。
[Abstract]:Objective : To compare the clinical , laboratory , endoscopic , histopathological and imaging differences between ischemic colitis ( IC ) and ulcerative colitis ( UC ) , and to find the identification point of the two , so as to facilitate the clinical treatment of ischemic colitis and ulcerative colitis . Methods : 20 patients with ischemic colitis and 30 patients with ulcerative colitis were collected from January 2010 to December 2013 in the First Affiliated Hospital of Guangxi Medical University . The data of sex , age , duration , basic disease history , clinical manifestation , enteroscopy findings , histopathological characteristics and imaging were analyzed . Results : Compared with UC group ( P 0.05 ) , IC group C reactive protein level ( 30.54 卤 11.12 ) ng / ml was higher than that in UC group ( P 0.05 ) . Conclusion : The clinical course of IC is long , the disease course of UC is short , mucus and blood is the main , the limitation of IC lesion in endoscope is longitudinal , boundary clear , non - continuous , UC lesion is extensive , easy to involve rectum , ulcer is map - like , UC in pathological aspect can have adenomatoid hyperplasia , crypts inflammation and abscess , and is the main identification point of the two .

【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R574.62

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