86例OMOM胶囊内镜临床应用研究

发布时间：2018-03-04 00:36

本文选题：OMOM胶囊内镜　切入点：小肠疾病　出处：《宁夏医科大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的：探讨OMOM胶囊内镜对消化道疾病，尤其是小肠疾病的诊断价值及安全性，便于临床合理应用。方法：回顾性分析2009年9月-2013年12月在宁夏医科大学总医院消化内科行OMOM胶囊内镜检查的86例患者(包括不明原因消化道出血患者34例，不明原因腹痛、腹泻、腹胀及消瘦患者52例)的临床资料，对诊断结果进行相关统计学分析。结果： 1、胶囊内镜检出结果：86例患者均顺利完成检查，检查成功率100%（86/86）；共发现病变81例，病变总检出率为94.2%（81/86），有68例患者检出小肠病变，小肠疾病病变检出率79.1%(68/86)，其中OGIB组小肠病变检出率为91.2%，最常见的病变为小肠血管畸形，腹痛组小肠病变检出率为71.2%，病变以小肠炎最为多见，OMOM胶囊内镜也可以检出消化道系统（如食管、胃、结肠等）其他病变。老年和中青年患者小肠疾病检出率无明显差异（P=0.271），但CE对不明原因的消化道出血患者的小肠病变检出率明显高于腹痛组患者（P0.05）。在对OGIB患者经CE检查的时间窗进行对比后，出血停止2周内经CE检查患者的小肠疾病检出率与2周以上患者的小肠疾病检出率无显著性差异（P0.05）。肠道准备时肌注甲氧氯普胺（胃复安）可以促进胶囊通过幽门(P=0.028)，从而提高全小肠检查率，而对小肠运行时间无显著影响。 2、胶囊运行时间：胶囊在胃内运行时间为1.3min-333min，平均运行时间为42.50min（M），在小肠内运行时间47min-566min，平均运行时间为284.00min（M）。 3、胶囊内镜检查的安全性及可靠性：OMOM胶囊内镜性能稳定，图像清晰，，摄像胶囊所携带的电池一般能满足对全小肠的观察。所有患者无一例出现胶囊滞留，且均未出现其他不良反应。结论： OMOM胶囊内镜检查安全、有效，对消化道疾病，特别是小肠疾病有良好的诊断价值，尤其适用于不明原因消化道出血的患者。
[Abstract]:Objective:. To investigate the diagnostic value and safety of OMOM capsule endoscopy for digestive tract diseases, especially small intestinal diseases, and to facilitate its clinical and rational application. Methods:. From September 2009 to December 2013, 86 patients (including 34 patients with unknown gastrointestinal bleeding, unknown abdominal pain and diarrhea) who were examined by OMOM capsule endoscopy in the Department of Digestive Medicine, Ningxia Medical University General Hospital, were retrospectively analyzed. The clinical data of 52 patients with abdominal distension and wasting were analyzed statistically. Results:. 1. The results of capsule endoscopy were as follows: 86 cases of patients were successfully completed, and the success rate was 100% 86%. 81 cases of lesions were found, the total detection rate of lesions was 94.2% 81 / 86%, 68 cases of small bowel lesions were detected. The detection rate of small intestinal diseases was 79.1% / 86%, and the detection rate of small intestinal lesions in OGIB group was 91.2%. The most common lesions were small intestinal vascular malformations. In the abdominal pain group, the detection rate of intestinal lesions was 71.2%. The most common lesions were small enteritis. OMOM capsule endoscopy could also detect gastrointestinal system (such as esophagus, stomach, stomach). There was no significant difference in the detection rate of intestinal diseases between aged and young patients, but the detection rate of intestinal lesions in patients with unknown gastrointestinal bleeding was significantly higher than that in patients with abdominal pain (P 0.05). In OGIB patients with CE, the detection rate of intestinal diseases was significantly higher than that of patients with abdominal pain. After comparing the time window of the inspection, There was no significant difference between the detection rate of intestinal diseases in patients with CE examination and those of patients over 2 weeks after bleeding cessation (P 0.05). Intramuscular injection of metoclopramide (metoclopramide) during intestinal preparation could promote capsule passage through pylorus. In order to improve the examination rate of the whole small intestine, However, there was no significant effect on the operation time of small intestine. 2, the running time of capsule: the running time of capsule in stomach was 1.3min-333min, the average running time was 42.50min, the running time in small intestine was 47min-566min, the average time was 284.00min. 3. The safety and reliability of the capsule endoscopy were stable, the images were clear, the battery carried by the camera capsule could generally satisfy the observation of the whole small intestine. None of the patients had capsule retention. There were no other adverse reactions. Conclusion:. OMOM capsule endoscopy is safe and effective, and has good diagnostic value for gastrointestinal diseases, especially small intestinal diseases, especially for patients with unknown gastrointestinal bleeding.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R574

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