重症监护室抗生素相关性腹泻流行现状与治疗

发布时间：2018-03-05 17:48

本文选题：ICU　切入点：危重症患者　出处：《现代预防医学》2015年09期 　论文类型：期刊论文

【摘要】：目的探讨重症监护室(ICU)住院患者抗生素相关性腹泻(AAD)的发生情况及其临床诊疗情况。方法针对2013年4月-2013年10月期间我院ICU、神外ICU所有出科患者,采用回顾性调查方法,调查抗生素使用情况、AAD的发生情况以及诊疗情况。此次仅统计包括抗生素类及合成抗菌药物类在内的抗菌药物的使用情况,抗结核药、抗真菌药、抗病毒药、抗寄生虫药不在观察范围内。结果一共835例患者纳入调查,210例患者发生AAD,AAD的发生率为25.15%;抗生素使用率为82.04%,在使用抗生素人群中AAD发生率为30.66%(210/685)。37.6%AAD患者未得到任何治疗AAD措施;而在治疗AAD人群中,常用的3种治疗AAD措施(益生菌、止泻药、益生菌联合止泻药),治疗AAD效果组间差异未见统计学意义(P0.05)。结论危重症患者的AAD发生率较高,但是并未引起临床医生重视,常见治疗手段效果也并不理想。在未来,需重视对AAD的预防。
[Abstract]:Objective to investigate the incidence and clinical diagnosis and treatment of antibiotic associated diarrhea (AAD) in inpatients with ICU in intensive care unit (ICU). Methods from April 2013 to October 2013, all patients with ICU and ICU were investigated retrospectively. Investigate the use of antibiotics and the occurrence and diagnosis and treatment of AAD. This time only statistics on the use of antimicrobial drugs, including antibiotics and synthetic antimicrobial agents, antituberculosis, antifungal, antiviral, Results the incidence of AAD-AAD in 210 patients was 25.15, the rate of antibiotic use was 82.044.The incidence of AAD was 30.6610 / 6850.37.6 D patients did not receive any treatment measures for AAD-AAD, and the incidence of antiparasitic drugs was not within the scope of observation. The incidence of AAD-AAD was 25.15, and the rate of antibiotic use was 82.044.The incidence of AAD was 30.6610 / 6850.37.6 D patients were not treated with AAD. In the treatment of AAD, there were three kinds of measures (probiotics, anti-diarrhea drugs, probiotics combined with anti-diarrhea drugs) in the treatment of AAD. There was no significant difference in the effect of AAD treatment between groups. Conclusion the incidence of AAD in critically ill patients is higher than that in the control group. But it has not attracted the attention of clinicians, and the effect of common treatment is not ideal. In the future, attention should be paid to the prevention of AAD.
【作者单位】：四川大学华西公共卫生学院(华西第四医院);四川大学华西医院;
【基金】：国家自然科学基金项目(81372982)
【分类号】：R574.62

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