外周血炎症介质对重症急性胰腺炎继发肺部感染的辅助诊断价值

发布时间：2018-03-07 15:07

本文选题：重症急性胰腺炎　切入点：肺部感染　出处：《辽宁中医杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的:探讨血液学指标在预测重症急性胰腺炎合并肺部感染的临床诊断价值。方法:选择2013年1月—2015年6月在本院接受治疗的重症急性胰腺炎患者作为研究对象,依据患者是否伴有肺部感染将患者分为非感染组及感染组。检测对比两组外周血TNF-α、IL-10、CRP及降钙素原水平。结果:本研究共纳入非感染组48例;感染组45例。感染组患者的TNF-α、CRP、降钙素原均高于非感染组患者,差异具有统计学意义(P0.05)。ROC曲线分析显示,以21.44 ng/L为截点值,TNF-α诊断重症急性胰腺炎继发肺部感染的敏感性为80.00%,特异性为85.42%,曲线下面积为0.83;其结果优于CRP、降钙素原。结论:TNF-α、CRP、降钙素原是重症急性胰腺炎合并肺部感染中的诊断的可靠指标,其中TNF-α具有较高的特异性和敏感性,在预测重症急性胰腺炎合并肺部感染具有重要价值。
[Abstract]:Objective: to investigate the clinical diagnostic value of hematologic markers in predicting severe acute pancreatitis complicated with pulmonary infection. Methods: patients with severe acute pancreatitis who were treated in our hospital from January 2013 to June 2015 were selected as study objects. The patients were divided into non-infection group and infected group according to whether the patients were accompanied with pulmonary infection. The levels of TNF- 伪 IL-10 CRP and procalcitonin in peripheral blood were measured and compared between the two groups. Results: 48 cases of non-infection group were included in this study. The TNF- 伪 CRP and procalcitonin levels in the infected group were significantly higher than those in the non-infected group, and the difference was statistically significant. Using 21.44 ng/L as the cut-off point, the sensitivity of TNF- 伪 in the diagnosis of pulmonary infection secondary to severe acute pancreatitis was 80.00g, the specificity was 85.42, and the area under the curve was 0.83.The results were superior to that of CRP- 伪 and procalcitonin. Conclusion: TNF- 伪 is a severe acute pancreatitis complicated with pulmonary infection. Reliable indicators for diagnosis of partial infections, Among them, TNF- 伪 has high specificity and sensitivity, and has important value in predicting severe acute pancreatitis complicated with pulmonary infection.
【作者单位】：昆明医科大学第一附属医院;
【分类号】：R563.1;R576

【相似文献】