血清GPC3和HSP70检测在乙肝相关肝癌诊断中的应用价值

发布时间：2018-03-12 10:05

  本文选题：肝癌诊断　切入点：GPC　出处：《中国地方病防治杂志》2017年07期 　论文类型：期刊论文

【摘要】：正目前主要应用甲胎蛋白(AFP)作为肝癌血清标志物。然而对于AFP的灵敏度报道不一,作为肝癌的诊断手段并不理想。据报道,磷脂酰肌醇聚糖3(GPC3)、热休克蛋白70(HSP70)有望成为肝细胞癌的早期诊断标志物[1]。为进一步确认GPC3和HSP70在乙肝相关肝癌诊断中的应用价值,本研究对GPC3、HSP70以及联合诊断的灵敏度和特异度进行了系统研究。1资料与方法
[Abstract]:Currently AFP is mainly used as a serum marker for liver cancer. However, the sensitivity of AFP is not reported to be satisfactory, and the diagnosis of HCC is not ideal. Phosphatidylinositol 3 (GPC3), heat shock protein 70 (HSP70) is expected to be an early diagnostic marker for hepatocellular carcinoma [1]. To further confirm the value of GPC3 and HSP70 in the diagnosis of Hepatitis B related liver cancer. In this study, the sensitivity and specificity of GPC3 HSP70 and its combined diagnosis were systematically studied. 1 data and methods
【作者单位】： 唐山市传染病医院;
【分类号】：R512.62;R735.7
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本文编号：1601085