孝感市HIV感染人群的戊肝血清流行病学特征分析

发布时间：2018-03-17 23:04

  本文选题：HIV　切入点：戊型肝炎病毒属　出处：《中华疾病控制杂志》2017年11期 　论文类型：期刊论文

【摘要】：目的了解孝感市人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染人群的戊型肝炎病毒(hepatitis E viral,HEV)流行情况,为更有效地开展艾滋病和戊肝防治工作提供科学依据。方法采集2015年5月~2016年9月203份HIV感染人群的血清样本,从中国疾病控制信息系统收集孝感市203名HIV感染人群的人口学资料、其他疾病感染史、实验室数据,血清进行抗-HEV IgG、抗-HEV IgM、HEV抗原(HEV antigen,HEVAg)筛查,并对抗-HEV Ig M阳性进行肝功能筛查。结果 203名HIV感染人群抗-HEV IgM阳性率为2.46%,抗-HEV IgG阳性率为46.31%(94/203)。抗-HEV IgG阳性率在性别上差异无统计学意义(X~2=0,P=0.996)。离异组抗-HEV IgG阳性率高达80%,与其他婚姻状况组的差异有统计学意义(均有P0.05)。CD4值≤200cell/μl的人群抗-HEV IgG阳性率与CD4200 cell/μl的人群抗-HEV Ig G阳性率差异无统计学意义(X~2=0.286,P=0.593);2个抗-HEV IgM阳性患者的CD4值分别为189 cell/μl和199 cell/μl,且1个肝功能异常。7个县市区抗-HEV IgG阳性率差异无统计学意义(醊2=5.906,P=0.551)。结论孝感市HIV感染人群HEV感染较高,积极开展两病双向筛查的同时需采取有针对性地预防和治疗措施。
[Abstract]:Objective to investigate the prevalence of hepatitis E virus hepatitis E virus (HEV) in the population infected with human immunodeficiency virus (immunodeficiency) in Xiaogan city. Methods from May 2015 to September 2016, the serum samples of 203patients with HIV infection were collected. The demographic data of 203 patients with HIV infection in Xiaogan City were collected from the China Disease Control Information system. The history of other diseases, laboratory data, serum anti-HEV IgG and anti-HEV IgM antigen were screened. Results the positive rates of anti-HEV IgM and anti-HEV IgG were 2.46 and 46.31%, respectively. The positive rate of anti-HEV IgG was 46.31 / 203. The positive rate of anti-HEV IgG was not significantly different in sex. The positive rate of anti-HEV IgG in divorced group was not statistically significant. There was no significant difference in the positive rate of anti-HEV IgG between the population with P0.05U. CD4 鈮，

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