血清PCT与炎症指标检测对肝硬化患者细菌感染的诊断价值分析

发布时间：2018-03-18 19:12

本文选题：肝硬化　切入点：降钙素原　出处：《中华医院感染学杂志》2017年21期 　论文类型：期刊论文

【摘要】：目的探讨血清降钙素原对肝硬化患者继发细菌感染的诊断价值。方法选取医院2011年1月-2016年8月收治的68例肝硬化患者的临床资料进行回顾性分析,根据患者是否合并细菌感染分为感染组23例和非感染组45例,对两组患者治疗前的血清降钙素原及其相关炎症指标进行比较分析。结果感染组患者血清PCT、hs-CRP、WBC以及N%水平均较非感染组患者明显增高,差异有统计学意义(P0.05);感染组不同感染类型患者的PCT、hs-CRP、WBC以及N%水平比较,差异无统计学意义;PCT和N%对诊断差异具有统计学意义(P0.05),23例患者共分离病原菌23株,以革兰阴性菌15株为主,占65.22%。结论肝硬化合并细菌感染早期血液检测可表现出明显的PCT水平升高,而PCT联合N%可作为判断肝硬化合并细菌感染的血液指标。
[Abstract]:Objective to investigate the value of serum procalcitonin in the diagnosis of secondary bacterial infection in patients with liver cirrhosis. Methods the clinical data of 68 patients with liver cirrhosis from January 2011 to August 2016 were retrospectively analyzed. According to whether the patients were complicated with bacterial infection, they were divided into infection group (n = 23) and non-infection group (n = 45). Serum procalcitonin and its related inflammatory indexes were compared between the two groups before treatment. Results the serum levels of PCThs-CRP WBC and N% in the infected group were significantly higher than those in the non-infected group. There was no significant difference in the levels of PCThs-CRPU WBC and N% in patients with different types of infection. There was no significant difference between PCT and N% in diagnosis. 23 strains of pathogenic bacteria were isolated from 23 patients with P0.05 infection, 15 of them were Gram-negative bacteria. Conclusion in the early stage of bacterial infection in cirrhotic patients, the level of PCT can be increased obviously, and PCT combined with N% can be used as a blood index for the diagnosis of bacterial infection in cirrhotic patients.
【作者单位】：昆明医科大学第一附属医院感染内科;
【基金】：云南省感染性疾病临床重点专科建设基金资助项目(2100201) 云南省科技厅-昆明医科大学联合专项基金资助项目(2015FB034)
【分类号】：R575.2

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