含呋喃唑酮方案对十二指肠溃疡患者幽门螺杆菌根除效果研究

发布时间：2018-03-21 12:03

本文选题：十二指肠溃疡　切入点：幽门螺杆菌　出处：《中华医院感染学杂志》2015年10期 　论文类型：期刊论文

【摘要】：目的探讨含呋喃唑酮方案对幽门螺杆菌(Hp)感染的十二指肠溃疡患者Hp根除效果,以降低Hp感染率。方法选取2010年3月-2014年3月Hp阳性十二指肠溃疡患者252例为研究对象,将患者按照不同治疗方案分为观察组和对照组,观察组给予含呋喃唑酮方案治疗,对照组给予不含呋喃唑酮的方案治疗,对比两组患者的Hp根除率、临床缓解情况、不良反应。结果观察组Hp根除率89.88%,高于对照组的77.38%,两组差异有统计学意义(P0.01);观察组临床症状缓解效果优于对照组,差异有统计学意义(P0.05);两组均未出现严重不良反应,观察组和对照组不良反应发生率差异无统计学意义。结论含呋喃唑酮方案可以提高Hp阳性十二指肠溃疡的Hp根除率,增强患者临床症状缓解效果,且安全性较高。
[Abstract]:Objective to explore the solution containing furazolidone on Helicobacter pylori (Hp) infection in patients with duodenal ulcer Hp eradication effect, to reduce the infection rate of Hp. Methods from March 2010 March -2014 Hp positive patients with duodenal ulcer in 252 cases as the research object, according to the different treatment were divided into observation group and control group, the observation group was treated with furazolidone treatment, the control group was given with furazolidone treatment, compared two groups of patients with Hp eradication rate, clinical remission, adverse reactions. Results the observation group Hp eradication rate of 89.88%, higher than 77.38% in the control group, there was significant difference between two groups (P0.01); the observation group clinical symptom relief effect better than the control group, the difference was statistically significant (P0.05); the two groups had no serious adverse reactions, the observation group and the control group adverse reaction rate was not statistically significant. Conclusion containing furazolidone solution can be provided The Hp eradication rate of high Hp positive duodenal ulcer increases the effect of clinical symptom relief and has high safety.

【作者单位】：浙江省立同德医院消化科;
【基金】：浙江省科技计划基金资助项目(2010C33019)
【分类号】：R573.1

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